Prediction of the Risk of Placental Vascular Pathology and Venous Thromboembolic Disease (AngioPred)
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Venous thromboembolic (VTE) disease is the first cause of maternal mortality in the world. Some other pregnancy pathologies called Placental Vascular Pathologies (PVP) are linked to VTE by biological thrombophilia and are the principal cause of perinatal mortality. the identification of predictive factors of risk of occurrence or recurrence of two pathologies could enable us to propose an appropriate monitoring of patients at risk.
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Ages Eligible for Study:
16 Years to 50 Years (Child, Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
previous history of one or more PVC episodes (preeclampsia, HELLPs, retroplacental hematoma, vascular IUGR<10th percentile, recurrence miscarriage >2, unexplained IUFD or IUFD after abruption placentae, eclampsia.
Previous history of personal VTE
Diabete (treated with diet or insulin)
chronic renal pathology
early and late pregnancy (<18 years, >38 years)
family history of cardiovascular disease of VTE
known biological thrombophilia without any personal past history of PVC or VTE
past history of in utero fetal death due to congenital malformations, rhesus incompatibility or an infection
previous history of IUGR which etiology was a chromosomal, genic or infectious anomaly