Physical Activity Following Surgery Induced Weight Loss
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|ClinicalTrials.gov Identifier: NCT00692367|
Recruitment Status : Completed
First Posted : June 6, 2008
Last Update Posted : November 4, 2014
The primary objective of this study will be to determine the effects of physical activity in patients during substantial surgery-induced weight loss.
A randomized controlled physical activity intervention trial in a group of patients undergoing bariatric surgery for weight loss. The study will involve two sites with an active bariatric surgery program, which have a strong track record of bariatric surgery research. The study will include 160-200 subjects. Changes in the primary outcome variables will be determined in previous gastric bypass patients as a result of 6 months of moderate physical activity compared to an educational control group not engaged structured exercise.
|Condition or disease||Intervention/treatment||Phase|
|Obesity||Behavioral: Physical Activity||Not Applicable|
Show Detailed Description
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||128 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||None (Open Label)|
|Official Title:||Physical Activity Following Surgery Induced Weight Loss|
|Study Start Date :||December 2007|
|Actual Primary Completion Date :||November 2011|
|Actual Study Completion Date :||November 2012|
Structured exercise program
Behavioral: Physical Activity
1. Physical activity group: Subjects will be progressed to 4-5 days per week, 30-45 min per session (120-180 min per week) of moderate intensity exercise. 2. Control (educational) group: Subjects will receive their usual care following surgery that in addition to their weight loss.
- Insulin sensitivity, intramyocellular lipid, total body fat, total lean mass [ Time Frame: Twelve months ]
- Intra-muscular adipose tissue, abdominal fat, mitochondria content, fat oxidation [ Time Frame: Twelve months ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00692367
|United States, North Carolina|
|East Carolina University|
|Greenville, North Carolina, United States, 27858|
|United States, Pennsylvania|
|Montefiore Hospital, N807|
|Pittsburgh, Pennsylvania, United States, 15213|
|Principal Investigator:||Bret H Goodpaster, Ph.D.||University of Pittsburgh|