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Effect of Resistant Starch Type 4 on Glycemia and Insulin Sensitivity in Young Adults

This study has been completed.
MGP Ingredients, Inc
Information provided by:
Kansas State University Identifier:
First received: May 22, 2008
Last updated: May 28, 2008
Last verified: May 2008
This study tested the effects of resistant starch type 4 on blood sugar and hunger in young adults with Type 2 diabetes.

Condition Intervention
Dietary Supplement: Resistant starch type 4 - raw
Dietary Supplement: Resistant Starch Type 4 - Cooked
Dietary Supplement: Dextrose
Dietary Supplement: Puffed Wheat

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Double Blind (Participant, Outcomes Assessor)
Primary Purpose: Supportive Care
Official Title: Effect of Resistant Starch Type 4 on Glycemia and Insulin Sensitivity in Young Adults

Resource links provided by NLM:

Further study details as provided by Kansas State University:

Primary Outcome Measures:
  • Post-Prandial Metabolism [ Time Frame: Early morning ]

Enrollment: 13
Study Start Date: November 2006
Study Completion Date: December 2007
Primary Completion Date: May 2007 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: 1
Resistant Starch Type 4-Raw
Dietary Supplement: Resistant starch type 4 - raw
Dose: 80g bar containing Resistant Starch Type 4 - raw
Experimental: 2
Resistant Starch Type 4-cooked
Dietary Supplement: Resistant Starch Type 4 - Cooked
Dose: 80g bar containing Resistant Starch Type 4 - cooked
Active Comparator: 3
Puffed wheat
Dietary Supplement: Puffed Wheat
Dose: 80g bar containing puffed wheat cereal
Placebo Comparator: 4
Dietary Supplement: Dextrose
Dose: 7 oz of oral glucose tolerance beverage

Detailed Description:
To measure the blood glucose response, after an overnight fast, blood samples were collected before eating and at 15, 30, 45, 60, 90, and 120 minutes after each each bar. The incremental area under the curve was used to calculate the glycemic index and insulin sensitivity via minimal model.

Ages Eligible for Study:   18 Years to 35 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Apparently Healthy (not diagnosed with disease)
  • Young Adults (18-35)

Exclusion Criteria:

  • Diagnosed with diabetes or other metabolic disorders
  • Allergies to Wheat
  • Non-smokers
  Contacts and Locations
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Please refer to this study by its identifier: NCT00687960

United States, Kansas
Kansas State University
Manhattan, Kansas, United States, 66506
Sponsors and Collaborators
Kansas State University
MGP Ingredients, Inc
Principal Investigator: Mark Haub, Ph.D. Department of Human Nutrition
  More Information

Responsible Party: Mark Haub Ph.D., Department of Human Nutrition Identifier: NCT00687960     History of Changes
Other Study ID Numbers: KSU-HML-RSt2
Study First Received: May 22, 2008
Last Updated: May 28, 2008

Keywords provided by Kansas State University:

Additional relevant MeSH terms:
Insulin Resistance
Glucose Metabolism Disorders
Metabolic Diseases
Hypoglycemic Agents
Physiological Effects of Drugs processed this record on May 25, 2017