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Effect of Resistant Starch Type 4 on Glycemia and Insulin Sensitivity in Young Adults

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00687960
First Posted: June 2, 2008
Last Update Posted: June 2, 2008
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Collaborator:
MGP Ingredients, Inc
Information provided by:
Kansas State University
  Purpose
This study tested the effects of resistant starch type 4 on blood sugar and hunger in young adults with Type 2 diabetes.

Condition Intervention
Hyperglycemia Dietary Supplement: Resistant starch type 4 - raw Dietary Supplement: Resistant Starch Type 4 - Cooked Dietary Supplement: Dextrose Dietary Supplement: Puffed Wheat

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Double (Participant, Outcomes Assessor)
Primary Purpose: Supportive Care
Official Title: Effect of Resistant Starch Type 4 on Glycemia and Insulin Sensitivity in Young Adults

Resource links provided by NLM:


Further study details as provided by Kansas State University:

Primary Outcome Measures:
  • Post-Prandial Metabolism [ Time Frame: Early morning ]

Enrollment: 13
Study Start Date: November 2006
Study Completion Date: December 2007
Primary Completion Date: May 2007 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: 1
Resistant Starch Type 4-Raw
Dietary Supplement: Resistant starch type 4 - raw
Dose: 80g bar containing Resistant Starch Type 4 - raw
Experimental: 2
Resistant Starch Type 4-cooked
Dietary Supplement: Resistant Starch Type 4 - Cooked
Dose: 80g bar containing Resistant Starch Type 4 - cooked
Active Comparator: 3
Puffed wheat
Dietary Supplement: Puffed Wheat
Dose: 80g bar containing puffed wheat cereal
Placebo Comparator: 4
Dextrose
Dietary Supplement: Dextrose
Dose: 7 oz of oral glucose tolerance beverage

Detailed Description:
To measure the blood glucose response, after an overnight fast, blood samples were collected before eating and at 15, 30, 45, 60, 90, and 120 minutes after each each bar. The incremental area under the curve was used to calculate the glycemic index and insulin sensitivity via minimal model.
  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 35 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Apparently Healthy (not diagnosed with disease)
  • Young Adults (18-35)

Exclusion Criteria:

  • Diagnosed with diabetes or other metabolic disorders
  • Allergies to Wheat
  • Non-smokers
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00687960


Locations
United States, Kansas
Kansas State University
Manhattan, Kansas, United States, 66506
Sponsors and Collaborators
Kansas State University
MGP Ingredients, Inc
Investigators
Principal Investigator: Mark Haub, Ph.D. Department of Human Nutrition
  More Information

Responsible Party: Mark Haub Ph.D., Department of Human Nutrition
ClinicalTrials.gov Identifier: NCT00687960     History of Changes
Other Study ID Numbers: KSU-HML-RSt2
First Submitted: May 22, 2008
First Posted: June 2, 2008
Last Update Posted: June 2, 2008
Last Verified: May 2008

Keywords provided by Kansas State University:
Diabetes
Diet
Fiber
Age

Additional relevant MeSH terms:
Insulin Resistance
Hyperglycemia
Hyperinsulinism
Glucose Metabolism Disorders
Metabolic Diseases
Insulin
Hypoglycemic Agents
Physiological Effects of Drugs