This site became the new on June 19th. Learn more.
Show more Menu IMPORTANT: Listing of a study on this site does not reflect endorsement by the National Institutes of Health. Talk with a trusted healthcare professional before volunteering for a study. Read more... Menu IMPORTANT: Talk with a trusted healthcare professional before volunteering for a study. Read more... Menu
Give us feedback

Comparison of On-line and Off-line Measurements of Exhaled Nitric Oxide (NO)

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified August 2009 by Ziv Hospital.
Recruitment status was:  Not yet recruiting
Information provided by:
Ziv Hospital Identifier:
First received: May 26, 2008
Last updated: August 15, 2009
Last verified: August 2009
Asthma is a major health problem worldwide. The measurement of fractional exhaled nitric oxide (FENO) has been established as a valuable non invasive and simple tool in the diagnosis of asthma and may also act as a useful surrogate inflammatory marker on which to base treatment decisions in asthma management algorithms. The measurement is useful also in other respiratory diseases. Current methods of measuring FENO include on line measurements by heavy duty expensive analyzers which are not widely and easily available. Off line measurements of breath samples which can be analysed later may be a simple solution. We hypothesize tha toff line measurements of NO will be as reliable and valid as those measured on-line

Asthma Primary Ciliary Dyskinesia

Study Type: Observational
Study Design: Observational Model: Case-Crossover
Time Perspective: Prospective
Official Title: Comparison of On-line and Off-line Measurements of Exhaled NO

Resource links provided by NLM:

Further study details as provided by Ziv Hospital:

Primary Outcome Measures:
  • Off line measurement of exhaled NO [ Time Frame: Two types of breathing in the same day ]

Estimated Enrollment: 200
Study Start Date: July 2010
Estimated Study Completion Date: July 2011
Estimated Primary Completion Date: July 2011 (Final data collection date for primary outcome measure)

Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
General population bth healthy and with respiratory illness such as asthma, COPD, PCD, Rhinitis

Inclusion Criteria:

  • Volunteer to participate
  • Filed a short health questionnaire

Exclusion Criteria:

  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00686309

Contact: Israel Amirav, MD 972-4-682-8712

Pediatric Department, Ziv Medical Center Not yet recruiting
Safed, Israel
Contact: Israel Amirav, MD    972-4-682-8712   
Principal Investigator: Israel Amirav, MD         
Sponsors and Collaborators
Ziv Hospital
  More Information

Responsible Party: Israel Amirav, Ziv Medical center Identifier: NCT00686309     History of Changes
Other Study ID Numbers: HP8-295-R
Study First Received: May 26, 2008
Last Updated: August 15, 2009

Keywords provided by Ziv Hospital:
exhaled NO
off line
on line
Bland altman method

Additional relevant MeSH terms:
Ciliary Motility Disorders
Kartagener Syndrome
Movement Disorders
Central Nervous System Diseases
Nervous System Diseases
Neurologic Manifestations
Signs and Symptoms
Respiratory Tract Diseases
Otorhinolaryngologic Diseases
Bronchial Diseases
Respiratory System Abnormalities
Heart Defects, Congenital
Cardiovascular Abnormalities
Cardiovascular Diseases
Heart Diseases
Congenital Abnormalities
Situs Inversus
Genetic Diseases, Inborn processed this record on September 21, 2017