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Comparison of On-line and Off-line Measurements of Exhaled Nitric Oxide (NO)

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified August 2009 by Ziv Hospital.
Recruitment status was:  Not yet recruiting
Sponsor:
ClinicalTrials.gov Identifier:
NCT00686309
First Posted: May 29, 2008
Last Update Posted: August 18, 2009
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
Ziv Hospital
  Purpose
Asthma is a major health problem worldwide. The measurement of fractional exhaled nitric oxide (FENO) has been established as a valuable non invasive and simple tool in the diagnosis of asthma and may also act as a useful surrogate inflammatory marker on which to base treatment decisions in asthma management algorithms. The measurement is useful also in other respiratory diseases. Current methods of measuring FENO include on line measurements by heavy duty expensive analyzers which are not widely and easily available. Off line measurements of breath samples which can be analysed later may be a simple solution. We hypothesize tha toff line measurements of NO will be as reliable and valid as those measured on-line

Condition
Asthma Primary Ciliary Dyskinesia

Study Type: Observational
Study Design: Observational Model: Case-Crossover
Time Perspective: Prospective
Official Title: Comparison of On-line and Off-line Measurements of Exhaled NO

Resource links provided by NLM:


Further study details as provided by Ziv Hospital:

Primary Outcome Measures:
  • Off line measurement of exhaled NO [ Time Frame: Two types of breathing in the same day ]

Estimated Enrollment: 200
Study Start Date: July 2010
Estimated Study Completion Date: July 2011
Estimated Primary Completion Date: July 2011 (Final data collection date for primary outcome measure)
  Eligibility

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
General population bth healthy and with respiratory illness such as asthma, COPD, PCD, Rhinitis
Criteria

Inclusion Criteria:

  • Volunteer to participate
  • Filed a short health questionnaire

Exclusion Criteria:

  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00686309


Contacts
Contact: Israel Amirav, MD 972-4-682-8712 amirav@012.net.il

Locations
Israel
Pediatric Department, Ziv Medical Center Not yet recruiting
Safed, Israel
Contact: Israel Amirav, MD    972-4-682-8712    amirav@012.net.il   
Principal Investigator: Israel Amirav, MD         
Sponsors and Collaborators
Ziv Hospital
  More Information

Responsible Party: Israel Amirav, Ziv Medical center
ClinicalTrials.gov Identifier: NCT00686309     History of Changes
Other Study ID Numbers: HP8-295-R
First Submitted: May 26, 2008
First Posted: May 29, 2008
Last Update Posted: August 18, 2009
Last Verified: August 2009

Keywords provided by Ziv Hospital:
exhaled NO
off line
on line
comparison
Bland altman method

Additional relevant MeSH terms:
Dyskinesias
Ciliary Motility Disorders
Kartagener Syndrome
Movement Disorders
Central Nervous System Diseases
Nervous System Diseases
Neurologic Manifestations
Signs and Symptoms
Respiratory Tract Diseases
Otorhinolaryngologic Diseases
Ciliopathies
Abnormalities, Multiple
Congenital Abnormalities
Genetic Diseases, Inborn
Bronchiectasis
Bronchial Diseases
Respiratory System Abnormalities
Dextrocardia
Heart Defects, Congenital
Cardiovascular Abnormalities
Cardiovascular Diseases
Heart Diseases
Situs Inversus