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Cognitive Therapy for PTSD in Addiction Treatment

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00685451
Recruitment Status : Completed
First Posted : May 28, 2008
Last Update Posted : September 29, 2011
National Institute on Drug Abuse (NIDA)
Information provided by:
Dartmouth-Hitchcock Medical Center

Brief Summary:
The purpose of this phase of the study is to assess the feasibility of a cognitive behavioral therapy for post-traumatic stress disorder (PTSD) in persons receiving outpatient services at an addiction treatment program. The next phase of the study will be a more rigorous investigation of the efficacy of the PTSD therapy within addiction treatment settings.

Condition or disease Intervention/treatment Phase
Stress Disorders, Post Traumatic Substance-Related Disorders Behavioral: Cognitive Behavioral Therapy (CBT) Phase 1 Phase 2

  Show Detailed Description

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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 49 participants
Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Cognitive Therapy for PTSD in Addiction Treatment
Study Start Date : November 2004
Actual Primary Completion Date : August 2006
Actual Study Completion Date : November 2006

Primary Outcome Measures :
  1. decrease in substance use at post-therapy and 3 month follow-up
  2. reduction in PTSD symptoms at post-therapy and 3 month follow-up
  3. improvement in addiction treatment retention

Secondary Outcome Measures :
  1. examine impact of depression, anxiety, and borderline personality disorder on outcomes
  2. explore impact of motivation and treatment readiness on outcomes
  3. assess overall level of satisfaction with treatment on outcomes
  4. examine impact of other services received on outcomes

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • At least 18 years old;
  • Actively enrolled in intensive outpatient addiction services;
  • Diagnosis of PTSD; and
  • Willing and able to provide informed consent.

Exclusion Criteria:

  • Acute psychotic disorder;
  • Psychiatric hospitalization or suicide attempt in the past 2 months;
  • Known impending court appearance or legal circumstance that may result in incarceration within next 8 months; and
  • Known medical condition that would likely cause study withdrawal in the next 8 months.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00685451

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United States, New Hampshire
Fresh Start at Concord Hospital
Concord, New Hampshire, United States, 03301
Farnum Center
Manchester, New Hampshire, United States, 03104
United States, Vermont
Quitting Time
Wilder, Vermont, United States, 05088
Sponsors and Collaborators
Dartmouth-Hitchcock Medical Center
National Institute on Drug Abuse (NIDA)
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Principal Investigator: Mark P. McGovern, Ph.D. Dartmouth-Hitchcock Medical Center

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Responsible Party: Mark P. McGovern, Ph.D., Principal Investigator, Dartmouth Medical School Identifier: NCT00685451     History of Changes
Other Study ID Numbers: 5K23DA016574 ( U.S. NIH Grant/Contract )
5K23DA016574 ( U.S. NIH Grant/Contract )
First Posted: May 28, 2008    Key Record Dates
Last Update Posted: September 29, 2011
Last Verified: September 2011
Keywords provided by Dartmouth-Hitchcock Medical Center:
cognitive behavior therapy
Additional relevant MeSH terms:
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Substance-Related Disorders
Behavior, Addictive
Stress Disorders, Post-Traumatic
Pathologic Processes
Stress Disorders, Traumatic
Trauma and Stressor Related Disorders
Mental Disorders
Compulsive Behavior
Impulsive Behavior
Chemically-Induced Disorders