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Contingency Management for Smoking in Substance Abusers (R21)

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ClinicalTrials.gov Identifier: NCT00683033
Recruitment Status : Completed
First Posted : May 23, 2008
Last Update Posted : November 21, 2011
Sponsor:
Collaborator:
National Institute on Drug Abuse (NIDA)
Information provided by (Responsible Party):
UConn Health

Brief Summary:
Patients (N=102) who meet diagnostic criteria for alcohol, cocaine, marijuana, or opiate abuse or dependence will meet with research staff on two days for quit preparation sessions (2 per day). These sessions include testing a breath sample for evidence of smoking twice each day (separated by at least 5 hours), counseling based on Public Health Service (PHS) guidelines for quitting smoking during the second session each day, and setting a quit date. After these sessions, participants will be randomly assigned to one of two 4-week conditions: (a) standard care or (b) standard care plus prize CM for smoking abstinence with the opportunity to win prizes for submitting samples that meet smoking abstinence criteria (e.g., CO ≤ 6ppm; cotinine ≤ 30ng/mL). Nicotine withdrawal and related measures will be assessed throughout the intervention. Follow-up data will be collected through 6-months post-quit date.

Condition or disease Intervention/treatment Phase
Cigarette Smoking Behavioral: Contingency Management Behavioral: Brief smoking cessation counseling Phase 2

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 51 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Contingency Management for Smoking in Substance Abusers
Study Start Date : May 2008
Actual Primary Completion Date : October 2010
Actual Study Completion Date : October 2010

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Arm Intervention/treatment
Active Comparator: A
Brief counseling based on public health service guidelines.
Behavioral: Brief smoking cessation counseling
For 4 weeks starting on the quit date, daily brief (about 5 minutes) counseling based on public health service guidelines for quitting smoking. Expired carbon monoxide tests are conducted twice daily and urinary cotinine tests are conducted once each week.
Experimental: B
Brief counseling based on public health service guidelines for quitting smoking plus prize-based contingency management
Behavioral: Contingency Management
For 4 weeks starting on the quit date, daily brief (about 5 minutes) counseling based on public health service guidelines for quitting smoking is delivered. Expired carbon monoxide (CO) tests are conducted twice daily and urinary cotinine tests are conducted once each week. Participants earn the opportunity to win prizes for submitting samples that meet smoking abstinence criteria (e.g., CO ≤ 6ppm; cotinine ≤ 30ng/mL).
Behavioral: Brief smoking cessation counseling
For 4 weeks starting on the quit date, daily brief (about 5 minutes) counseling based on public health service guidelines for quitting smoking. Expired carbon monoxide tests are conducted twice daily and urinary cotinine tests are conducted once each week.



Primary Outcome Measures :
  1. Cigarette smoking abstinence. [ Time Frame: Daily through the 4-week intervention and at follow-up interviews 1, 2, 3, and 6 months following the quit date. ]


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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • current alcohol, cocaine, marijuana, or opiate abuse or dependence
  • smoke ≥ 10 cigarettes per day
  • expired CO > 8 ppm
  • self-reported interest in quitting smoking,
  • ≥ 18 years old
  • willing to provide names, addresses and phone numbers of individuals to assist in locating the participant for follow-up evaluations,
  • English speaking

Exclusion Criteria:

  • currently receiving behavioral therapy or pharmacotherapy for smoking plan to use pharmacotherapy in this quit attempt
  • serious, uncontrolled psychiatric illness (e.g., acute schizophrenia, suicide risk)
  • cognitive impairment
  • in recovery for pathological gambling

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00683033


Locations
United States, Connecticut
University of Connecticut Health Center
Farmington, Connecticut, United States, 06030
Sponsors and Collaborators
UConn Health
National Institute on Drug Abuse (NIDA)
Investigators
Principal Investigator: Sheila M Alessi, Ph.D. UConn Health

Responsible Party: UConn Health
ClinicalTrials.gov Identifier: NCT00683033     History of Changes
Other Study ID Numbers: 08-081-2
R21DA021836-01A2 ( U.S. NIH Grant/Contract )
First Posted: May 23, 2008    Key Record Dates
Last Update Posted: November 21, 2011
Last Verified: November 2011

Keywords provided by UConn Health:
Contingency Management
Cigarette Smoking Cessation
Substance Abusers