Hemodynamic Changes During Normal Pregnancy

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00682201
Recruitment Status : Completed
First Posted : May 22, 2008
Last Update Posted : July 6, 2011
Information provided by:
Oslo University Hospital

Brief Summary:
Prospective, observational study of the changes in hemodynamic variables such as blood pressure, cardiac output, systemic vascular resistance, and of changes in respiratory variables such as vital capacity, and functional residual volume.A cohort study of 100 healthy pregnant women tested with non-invasive methods during pregnancy and 6 months after delivery.

Condition or disease

Detailed Description:
Healthy pregnant women with the willingness to consent in physiologic tests at 3 different time points during, and one time point after pregnancy. Spirometric tests will be performed with V-MAX, non-invasive measuring of hemodynamics will be measured by Finometer.

Study Type : Observational
Estimated Enrollment : 120 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Hemodynamic Changes During Normal Pregnancy: A Prospective Cohort Study of 100 Healthy Pregnant Women
Study Start Date : August 2007
Actual Primary Completion Date : June 2009
Actual Study Completion Date : June 2009

Healthy pregnant women

Primary Outcome Measures :
  1. Pregnancy specific changes in hemodynamic variables [ Time Frame: Normal pregnancy time frame ]

Secondary Outcome Measures :
  1. Respiratory functional changes [ Time Frame: Normal pregnancy time frame ]

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

Ages Eligible for Study:   18 Years to 35 Years   (Adult)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Healty pregnant women scheduled for delivery at the Birth Clinic, Rikshospitalet University Hospital.

Inclusion Criteria:

  • Pregnant women who at first admission are healthy

Exclusion Criteria:

  • Co-existing diseases who represents decreased physical or psychological function

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00682201

Rikshospitalet University Hospital, Division of Anesthesia and Critical Care Medicine
Oslo, Norway, 0027
Sponsors and Collaborators
Oslo University Hospital
Study Director: Leiv Arne Rosseland, PhD MD Rikshospitalet University Hospital

Responsible Party: Øyvind Skraastad, Head of The Division of Anaesthesia and Intensive Care Medicine, Rikshospitalet University Hospital, Oslo, Norway Identifier: NCT00682201     History of Changes
Other Study ID Numbers: storkhemo-08-GG
First Posted: May 22, 2008    Key Record Dates
Last Update Posted: July 6, 2011
Last Verified: June 2009

Keywords provided by Oslo University Hospital:
Blood pressure
Cardiac output