Metabolic Derangements in Acute Heart Failure Syndrome
This study has been terminated.
(Project not initiated)
Sponsor:
The Cleveland Clinic
Information provided by:
The Cleveland Clinic
ClinicalTrials.gov Identifier:
NCT00682175
First received: May 20, 2008
Last updated: March 25, 2009
Last verified: March 2009
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Purpose
To determine the association of both neurohormonal and hemodynamic alterations associated with metabolic abnormalities in acute heart failure syndrome.
| Condition | Intervention |
|---|---|
|
Congestive Heart Failure |
Other: Observational |
| Study Type: | Observational |
| Study Design: | Observational Model: Case-Only Time Perspective: Prospective |
| Official Title: | Metabolic Derangements in Acute Heart Failure Syndrome |
Resource links provided by NLM:
Further study details as provided by The Cleveland Clinic:
Biospecimen Retention: Samples Without DNA
serum, plasma
| Estimated Enrollment: | 100 |
| Study Start Date: | May 2008 |
| Study Completion Date: | March 2009 |
| Primary Completion Date: | March 2009 (Final data collection date for primary outcome measure) |
| Groups/Cohorts | Assigned Interventions |
|---|---|
|
Observation
Adult (age > 18 yrs) patients admitted to the Heart Failure Intensive Care Unit with Acute Heart Failure Syndrome requiring placement of a Pulmonary Artery catheter for hemodynamically guided therapy.
|
Other: Observational
Pulmonary Artery pressure (PA), pulmonary capillary wedge pressure (PCWP), cardiac output (CO), and cardiac index (CI). This data will be collected after 24 ± 2 and 48 ± 2 hours of standard heart failure therapy
|
Eligibility| Ages Eligible for Study: | 18 Years and older (Adult, Senior) |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
| Sampling Method: | Non-Probability Sample |
Study Population
Adult (age > 18 yrs) patients admitted to the Heart Failure Intensive Care Unit (H22) with Acute Heart Failure Syndrome (AHFS) requiring placement of a Pulmonary Artery catheter for hemodynamically guided therapy.
Criteria
Inclusion Criteria:
- Adult (age > 18 yrs) patients admitted to the Heart Failure Intensive Care Unit (H22) with Acute Heart Failure Syndrome (AHFS) requiring placement of a Pulmonary Artery catheter for hemodynamically guided therapy.
Exclusion Criteria:
- History of Congenital Heart Disease.
- Acute HF in the setting of acute myocardial infarction.
- Severe Anemia
- Patients listed for cardiac transplantation.
- Terminal Malignancy, AIDS or CNS disease.
- Concomitant sepsis, ARDS, trauma, aortic dissection, or pericardial tamponade
Contacts and Locations
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To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below.
For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00682175
Please refer to this study by its ClinicalTrials.gov identifier: NCT00682175
Sponsors and Collaborators
The Cleveland Clinic
Investigators
| Principal Investigator: | George Sokos, MD | The Cleveland Clinic |
More Information
| Responsible Party: | George Sokos, MD, Cleveland Clinic Foundation |
| ClinicalTrials.gov Identifier: | NCT00682175 History of Changes |
| Other Study ID Numbers: | 08-169 |
| Study First Received: | May 20, 2008 |
| Last Updated: | March 25, 2009 |
| Health Authority: | United States: Institutional Review Board |
Keywords provided by The Cleveland Clinic:
|
Congestive Heart Failure |
Additional relevant MeSH terms:
|
Heart Failure Metabolic Diseases Heart Diseases Cardiovascular Diseases |
ClinicalTrials.gov processed this record on September 23, 2016