Cytomegalovirus (CMV) MicroRNA Expression in Vivo and Immune Evasion Correlates
Cytomegalovirus (CMV) is the most common viral infection in patients who have undergone a transplant.Serious infections due to CMV can affect many parts of the body including the lungs, the gut, and the liver. The purpose of this study is to assess how the virus interacts with the patient's immune system, so that in the future it may be possible to develop better ways to prevent and treat the virus infection.
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Cytomegalovirus (CMV) microRNA Expression in Vivo and Immune Evasion Correlates|
|Study Start Date:||April 2008|
|Estimated Study Completion Date:||December 2016|
|Estimated Primary Completion Date:||July 2016 (Final data collection date for primary outcome measure)|
Solid organ transplant recipients with both asymptomatic CMV viremia, and symptomatic CMV disease are eligible for inclusion in the study. THis includes liver, kidney, heart, pancreas, lung, intestinal and combined transplant recipients.
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Please refer to this study by its ClinicalTrials.gov identifier: NCT00677482
|University of Alberta Hospital|
|Edmonton, Alberta, Canada, T6G-2E1|
|Principal Investigator:||Atul Humar, MD||University of Alberta|