Study of the Treatment of Burn Wounds With Antimicrobial Topical Soaks
Determine effectiveness of various antimicrobial solutions on burn wounds (infections, wound healing, length of hospital stay).
|Study Design:||Endpoint Classification: Safety/Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
|Official Title:||Comparing the Use of Sulfamylon 5%, Dakins 0.025%, Cerium, Silver Nitrate 5% and/or Other Topical Antimicrobial Products for the Treatment of Excised and/or Grafted Burn Wounds|
- Infection Rate [ Time Frame: Acute hospitalization following burn injury: admission to discharge (1-20 weeks) ] [ Designated as safety issue: No ]Percent of infections following antimicrobial topical treatment with Sulfamylon vs Silver Nitrate Soaks.
- Length of Hospital Stay With Various Antimicrobial Solutions for Burn Patients [ Time Frame: Admission to burn unit to discharge ] [ Designated as safety issue: No ]
|Study Start Date:||July 1995|
|Study Completion Date:||May 2008|
|Primary Completion Date:||May 2008 (Final data collection date for primary outcome measure)|
Experimental: Sulfamylon 5% and Silver Nitrate Soaks
Application of Sulfamylon 5% Solution and Silver Nitrate soaked dressings to two different burned area. Sites were then monitored for infections during hospitalization.
Drug: Sulfamylon 5% and Silver Nitrate Soaks
Application of Sulfamylon and Silver Nitrate Solution to burn wound daily
Patients were treated with both Sulfamylon soaks and Silver nitrate soaks on different burn areas. These two areas were then compared for incidence (percentage) of infections.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00675922
|United States, Texas|
|University of Texas Medical Branch|
|Galveston, Texas, United States, 77555|
|Principal Investigator:||David N Herndon, MD||University of Texas|