Isokinetic Testing Protocol in Elderly and Young Men

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00673998
Recruitment Status : Completed
First Posted : May 7, 2008
Last Update Posted : May 7, 2008
Information provided by:
University of Brasilia

Brief Summary:
An age-related decrease in muscular strength may have a detrimental effect on muscle fatigue and recovery. To date, only one study has determined the effect of varied rest intervals (RI) between exercise sets in active younger and older women. They reported that active younger and older women require similar RI between sets to recovery full isokinetic knee extension peak torque (PT). However, we are unaware of any published studies comparing RI PT recovery between younger and older men. Thus, the purpose of this study was to compare the effect of two different RI's between sets of isokinetic knee extension exercise on PT, and Total Work (TW) between untrained younger and older men.

Condition or disease Intervention/treatment Phase
Healthy Device: Isokinetic Dynamometer (Biodex system III) Not Applicable

Detailed Description:
18 young men (24.22 ± 2.58 yrs) and 20 older men (66.85 ± 4.02 yrs) performed 3 sets of 10 unilateral isokinetic knee extension repetitions at 60°/s. The rest intervals between sets were 1 and 2 minutes and were counterbalanced across 2 testing days, separated by a minimum of 48 hours. The work-to-rest ratio was 1:3 and 1:6. All subjects were not involved in exercise programs that included resistance exercises within the last 6 months. Statistical evaluation of the data was performed using a 2x 2 x 3 mixed factor repeated measures ANOVA [age (younger and older) x rest interval (1 and 2 min) x set (1st, 2nd, and 3rd)]. Statistical significance was set at p < 0.05 for all comparisons.

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 38 participants
Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Diagnostic
Official Title: The Effects of Rest Interval on Quadriceps Torque During an Isokinetic Testing Protocol in Elderly and Young Men
Study Start Date : February 2005
Actual Primary Completion Date : March 2006
Actual Study Completion Date : November 2006

Intervention Details:
  • Device: Isokinetic Dynamometer (Biodex system III)
    Biodex system III Isokinetic Dynamometer (Biodex Medical, Inc., Shirley, NY).
    Other Names:
    • Biodex Isokinetic Dynamometer
    • Cybex Isokinetic Dynamometer

Primary Outcome Measures :
  1. Peak Torque [ Time Frame: 1 week ]

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Ages Eligible for Study:   20 Years to 75 Years   (Adult, Older Adult)
Sexes Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Less than 75 years
  • Independent

Exclusion Criteria:

  • History of cardiovascular disease
  • Hypertension
  • Orthopedic disease

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00673998

University of Brasilia
Brasilia, DF, Brazil, 70919-970
Sponsors and Collaborators
University of Brasilia
Principal Investigator: Martim Bottaro, PhD University of Brasilia

Responsible Party: Martim Bottaro, PhD, University of Brasilia Identifier: NCT00673998     History of Changes
Other Study ID Numbers: UCB-072/2004
First Posted: May 7, 2008    Key Record Dates
Last Update Posted: May 7, 2008
Last Verified: May 2008

Keywords provided by University of Brasilia: