The Role of Narrow-Band Imaging Endoscopy in Diagnosing Gastric Intestinal Metaplasia

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00673699
Recruitment Status : Unknown
Verified May 2008 by Hillel Yaffe Medical Center.
Recruitment status was:  Not yet recruiting
First Posted : May 7, 2008
Last Update Posted : May 7, 2008
Information provided by:
Hillel Yaffe Medical Center

Brief Summary:
The purpose of this study is to determine if endoscope with NBI(narrow banding imaging)can detect intestinal metaplasia( consider pre malignant condition) and use a targeting biopsy in case of suspected intestinal metaplasia

Condition or disease Intervention/treatment
Dyspepsia Procedure: Gastric mucosal biopsy

Detailed Description:
To detect intestinal metaplasia which consider pre malignant condition and use a targeting biopsy in case of suspected intestinal metaplasia which allowed us to better follow-up those patients.

Study Type : Observational
Estimated Enrollment : 70 participants
Observational Model: Case Control
Time Perspective: Prospective
Official Title: Observational: Studies in Human Beings Health Outcomes
Study Start Date : May 2008
Estimated Primary Completion Date : January 2009
Estimated Study Completion Date : February 2009

Resource links provided by the National Library of Medicine

Group/Cohort Intervention/treatment
Seventy dyspeptic consecutive patients that going upper gastrointestinal endoscopy
Procedure: Gastric mucosal biopsy
Using upper gastrointestinal endoscopy with targeting biopsy in patients with dyspepsia
Other Name: patients ith dyspepsia

Primary Outcome Measures :
  1. To determine if endoscope with NBI can detect intestinal metaplasia [ Time Frame: In one week (the time from biopsy till the histology assement) ]

Biospecimen Retention:   Samples Without DNA
Gastric mucosal biopsy during upper gastrointestinal endoscopy

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 75 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Hundred consecutive dyspeptic patients

Inclusion Criteria:

  • Dyspepsia

Exclusion Criteria:

  • Pregnancy,
  • Upper gastrointestinal bleeding,
  • Previous gastric operation,
  • Known gastric malignancy'
  • Non cooperative patients

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00673699

Contact: Zvi Fireman, MD +972-4-6304384
Contact: Yael Kopelman, MD +972-4-6304480

Hillel Yaffe Med Ctr Not yet recruiting
Hadera, Israel, 38100
Contact: Zvi Fireman, MD    +972-4-6304384   
Sub-Investigator: Yael Kopelman, MD         
Sponsors and Collaborators
Hillel Yaffe Medical Center
Principal Investigator: Zvi Fireman, MD Hillel Yaffe Med Ctr

Responsible Party: Zvi Fireman MD, Head ,Gastroenterology Dept., Zvi Fireman MD, Gastroenterology Dept. Hillel Yaffe Med Ctr Identifier: NCT00673699     History of Changes
Other Study ID Numbers: HY-07/2008
First Posted: May 7, 2008    Key Record Dates
Last Update Posted: May 7, 2008
Last Verified: May 2008

Keywords provided by Hillel Yaffe Medical Center:
intestinal metaplasia

Additional relevant MeSH terms:
Signs and Symptoms, Digestive
Signs and Symptoms
Pathologic Processes