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Adrenal Tumors - Pathogenesis and Therapy

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT00669266
Recruitment Status : Recruiting
First Posted : April 30, 2008
Last Update Posted : February 8, 2023
Sponsor:
Collaborators:
Deutsche Krebshilfe e.V., Bonn (Germany)
German Federal Ministry of Education and Research
Information provided by (Responsible Party):
Martin Fassnacht, University of Wuerzburg

Study Description
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Brief Summary:
The pathogenesis of adrenal tumors is still not fully elucidated and the treatment options for malignant tumors are poor. The current study investigates different aspects of the pathogenesis of adrenal tumors and evaluates different therapeutic options in patients with adrenocortical carcinoma.

Condition or disease
Adrenal Tumors Adrenocortical Carcinoma Cushing Syndrome Conn Syndrome Pheochromocytoma

Study Design
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Study Type : Observational
Estimated Enrollment : 500 participants
Observational Model: Case-Control
Time Perspective: Other
Official Title: Investigation of the Tumorigenesis of Adrenal Tumors and Evaluation of New Therapeutic Options - Untersuchungen Zur Tumorgenese Von Nebennierentumoren Und Evaluation Neuer Therapieoptionen
Actual Study Start Date : September 2002
Estimated Primary Completion Date : December 2030
Estimated Study Completion Date : December 2030

Resource links provided by the National Library of Medicine


Groups and Cohorts
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Group/Cohort
Tumor
Tumor material and corresponding biosamples from patients with adrenal tumors
control group
Biomaterial from patients without adrenal tumor


Outcome Measures
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Biospecimen Retention:   Samples With DNA
Germline DNA Tumor samples Serum Plasma Urine

Eligibility Criteria
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Information from the National Library of Medicine

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Ages Eligible for Study:   up to 100 Years   (Child, Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patients with adrenal tumors
Criteria

Inclusion Criteria:

  • adrenal tumor detected by imaging

Exclusion Criteria:

Contacts and Locations
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Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00669266


Contacts
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Contact: Martin Fassnacht, MD 49-931-201-36507 fassnacht_m@medizin.uni-wuerzburg.de

Locations
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Germany
University of Wuerzburg Recruiting
Wuerzburg, Germany, 97080
Contact: Martin Fassnacht, MD       fassnacht_m@medizin.uni-wuerzburg.de   
Contact: Stefanie Hahner, MD       hahner_s@medizin.uni-wuerzburg.de   
Principal Investigator: Martin Fassnacht, MD         
Sponsors and Collaborators
University of Wuerzburg
Deutsche Krebshilfe e.V., Bonn (Germany)
German Federal Ministry of Education and Research
Investigators
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Principal Investigator: Martin Fassnacht, MD U of Wuerzburg
More Information
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Publications of Results:

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Responsible Party: Martin Fassnacht, Head of Endocrinology, University of Wuerzburg
ClinicalTrials.gov Identifier: NCT00669266    
Other Study ID Numbers: Wue-Adrenal-Tumors-92/2002
First Posted: April 30, 2008    Key Record Dates
Last Update Posted: February 8, 2023
Last Verified: February 2023
Additional relevant MeSH terms:
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Cushing Syndrome
Pheochromocytoma
Adrenocortical Carcinoma
Adrenal Gland Neoplasms
Hyperaldosteronism
Syndrome
Disease
Pathologic Processes
Paraganglioma
Neuroendocrine Tumors
Neuroectodermal Tumors
Neoplasms, Germ Cell and Embryonal
Neoplasms by Histologic Type
 Neoplasms
Neoplasms, Nerve Tissue
Adrenocortical Hyperfunction
Adrenal Gland Diseases
Endocrine System Diseases
Adenocarcinoma
Carcinoma
Neoplasms, Glandular and Epithelial
Adrenal Cortex Neoplasms
Endocrine Gland Neoplasms
Neoplasms by Site
Adrenal Cortex Diseases