Adrenal Tumors - Pathogenesis and Therapy

This study is currently recruiting participants. (see Contacts and Locations)
Verified September 2015 by University of Wuerzburg
Deutsche Krebshilfe e.V., Bonn (Germany)
German Federal Ministry of Education and Research
Information provided by (Responsible Party):
Martin Fassnacht, University of Wuerzburg Identifier:
First received: April 28, 2008
Last updated: September 6, 2015
Last verified: September 2015

The pathogenesis of adrenal tumors is still not fully elucidated and the treatment options for malignant tumors are poor. The current study investigates different aspects of the pathogenesis of adrenal tumors and evaluates different therapeutic options in patients with adrenocortical carcinoma.

Adrenal Tumors
Adrenocortical Carcinoma
Cushing Syndrome
Conn Syndrome

Study Type: Observational
Study Design: Observational Model: Case Control
Official Title: Investigation of the Tumorigenesis of Adrenal Tumors and Evaluation of New Therapeutic Options - Untersuchungen Zur Tumorgenese Von Nebennierentumoren Und Evaluation Neuer Therapieoptionen

Resource links provided by NLM:

Further study details as provided by University of Wuerzburg:

Biospecimen Retention:   Samples With DNA

Germline DNA Tumor samples Serum Plasma Urine

Estimated Enrollment: 500
Study Start Date: September 2002
Estimated Study Completion Date: December 2024
Estimated Primary Completion Date: December 2022 (Final data collection date for primary outcome measure)
Tumor material and corresponding biosamples from patients with adrenal tumors
control group
Biomaterial from patients without adrenal tumor


Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

Patients with adrenal tumors


Inclusion Criteria:

  • adrenal tumor detected by imaging

Exclusion Criteria:

  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00669266

Contact: Martin Fassnacht, MD 49-931-201-36507

University of Wuerzburg Recruiting
Wuerzburg, Germany, 97080
Contact: Martin Fassnacht, MD   
Contact: Stefanie Hahner, MD   
Principal Investigator: Martin Fassnacht, MD         
Sponsors and Collaborators
University of Wuerzburg
Deutsche Krebshilfe e.V., Bonn (Germany)
German Federal Ministry of Education and Research
Principal Investigator: Martin Fassnacht, MD U of Wuerzburg
  More Information

No publications provided

Responsible Party: Martin Fassnacht, Head of Endocrinology, University of Wuerzburg Identifier: NCT00669266     History of Changes
Other Study ID Numbers: Wue-Adrenal-Tumors-92/2002
Study First Received: April 28, 2008
Last Updated: September 6, 2015
Health Authority: Germany: Ethics Commission

Additional relevant MeSH terms:
Adrenal Gland Neoplasms
Adrenocortical Carcinoma
Cushing Syndrome
Adrenal Cortex Diseases
Adrenal Cortex Neoplasms
Adrenal Gland Diseases
Adrenocortical Hyperfunction
Endocrine Gland Neoplasms
Endocrine System Diseases
Neoplasms by Histologic Type
Neoplasms by Site
Neoplasms, Germ Cell and Embryonal
Neoplasms, Glandular and Epithelial
Neoplasms, Nerve Tissue
Neuroectodermal Tumors
Neuroendocrine Tumors
Pathologic Processes processed this record on October 09, 2015