Neuropathic Pain Database (NePDatabase)
Recruitment status was Active, not recruiting
To establish the infrastructure for a national neuropathic pain database.
To determine the longterm outcome of the management of chronic neuropathic pain including pain relief, disability, and quality of life.
|Study Design:||Observational Model: Case-Only
Time Perspective: Prospective
|Official Title:||National Neuropathic Pain Database Study|
- To establish the infrastructure for a national Neuropathic Pain Database. [ Time Frame: 2 years ] [ Designated as safety issue: No ]To establish the infrastructure for a National Neuropathic Pain Database, with a composite primary outcome measure in average pain intensity (based on average pain intensity of BPI) and reduction in disability (based on Interference Scale Score of BPI))
- To determine the longterm outcome of the management of chronic neuropathic pain including pain relief, disability and quality of life. [ Time Frame: 2 years ] [ Designated as safety issue: No ]
|Study Start Date:||April 2008|
|Estimated Study Completion Date:||July 2012|
|Estimated Primary Completion Date:||June 2012 (Final data collection date for primary outcome measure)|
New patients with a diagnosis of Neuropathic Pain
The database will provide standard information on demographics, diagnosis, treatment interventions and outcome modeled on guidelines from the expert panel on initiatives on Methods, Measurement and Pain Assessment in Clinical Trials (IMMPACT)(Turk et al.,Pain 2003;106:337-345) The IMMPACT panel determined that patients should be evaluated according to six core domains as follows: Pain, physical functioning, emotional functioning, subject rating of global satisfaction with treatment, symptoms and adverse events and subject disposition.
The database will allow us to examine outcomes based on single (eg. pregabalin) and multiple (e.g tricyclic antidepressants and gabalin) therapeutic interventions. Standard guidelines for management of neuropathic pain acknowledge that polypharmacy is appropriate when individual first line treatments fail to provide adequate pain relief (Gilron I et al., CMAJ 2006; 175: 265-275; Attal N et al., European Journal of Neurology 2006; 13: 1153-1169)
Please refer to this study by its ClinicalTrials.gov identifier: NCT00669006
|London Health Sciences Centre- St. Joseph's Health Care|
|London, Ontario, Canada, N6A 4V2|
|Principal Investigator:||Dwight Moulin, MD||London Health Sciences Centre- St. Joseph's Health Care|