Type 2 Diabetes and Exercise - A Pilot Study
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|ClinicalTrials.gov Identifier: NCT00666861|
Recruitment Status : Terminated (Pilot study superseded by a larger NHMRC funded trial)
First Posted : April 25, 2008
Last Update Posted : July 30, 2009
A randomised, cross-over trial targeting a small sample of older (age 45-65 years) overweight adults with type 2 diabetes the aims of this pilot study are to:
- Determine the feasibility of investigating the acute effects of prolonged sedentary behaviour (sitting) in this target group.
- Compare the acute effects of a single prolonged (8 hour) bout of sedentary behaviour (sitting) on glucose and triglyceride concentrations and key muscle and adipose regulatory enzymes to a similar bout of sedentary behaviour combined with intermittent bouts of light-intensity activity.
|Condition or disease|
|Type 2 Diabetes|
The proposed study will involve a randomised cross-over experimental trial conducted in the laboratory setting in older overweight adults with type 2 diabetes. Participants will receive both of the acute testing conditions in a randomised manner.
Study design: Randomised cross-over pilot trial of 20 overweight/obese older adults with diet-controlled type 2 diabetes involving 2 acute treatment conditions, with a one-week wash-out period between testing conditions (Figure 1 a).
Setting: Acute, supervised laboratory setting within the Alfred and Baker Heart Institute Medical Unit.
Outcomes: We will measure acute responses in laboratory-measured plasma glucose & triglyceride levels (every 60 mins) and glucose concentrations determined from continuous glucose monitoring (CGMS).
|Study Type :||Observational|
|Actual Enrollment :||2 participants|
|Official Title:||Understanding the Acute Effects of Prolonged Sedentary Behaviour (Sitting) on Post-meal Glucose and Lipids - A Pilot Study|
|Study Start Date :||April 2008|
|Actual Primary Completion Date :||October 2008|
|Actual Study Completion Date :||November 2008|
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00666861
|Melbourne, Victoria, Australia, 3004|
|Principal Investigator:||Bronwyn A Kingwell, PhD||Baker Heart Research Institute|