Try our beta test site

Type 2 Diabetes and Exercise - A Pilot Study

This study has been terminated.
(Pilot study superseded by a larger NHMRC funded trial)
International Diabetes Institute, Australia
Baker Heart Research Institute
Information provided by:
Bayside Health Identifier:
First received: April 23, 2008
Last updated: July 28, 2009
Last verified: July 2009

A randomised, cross-over trial targeting a small sample of older (age 45-65 years) overweight adults with type 2 diabetes the aims of this pilot study are to:

  1. Determine the feasibility of investigating the acute effects of prolonged sedentary behaviour (sitting) in this target group.
  2. Compare the acute effects of a single prolonged (8 hour) bout of sedentary behaviour (sitting) on glucose and triglyceride concentrations and key muscle and adipose regulatory enzymes to a similar bout of sedentary behaviour combined with intermittent bouts of light-intensity activity.

Type 2 Diabetes

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Cross-Sectional
Official Title: Understanding the Acute Effects of Prolonged Sedentary Behaviour (Sitting) on Post-meal Glucose and Lipids - A Pilot Study

Further study details as provided by Bayside Health:

Biospecimen Retention:   Samples Without DNA
Plasma samples

Enrollment: 2
Study Start Date: April 2008
Study Completion Date: November 2008
Primary Completion Date: October 2008 (Final data collection date for primary outcome measure)
Detailed Description:

The proposed study will involve a randomised cross-over experimental trial conducted in the laboratory setting in older overweight adults with type 2 diabetes. Participants will receive both of the acute testing conditions in a randomised manner.

Study design: Randomised cross-over pilot trial of 20 overweight/obese older adults with diet-controlled type 2 diabetes involving 2 acute treatment conditions, with a one-week wash-out period between testing conditions (Figure 1 a).

Setting: Acute, supervised laboratory setting within the Alfred and Baker Heart Institute Medical Unit.

Outcomes: We will measure acute responses in laboratory-measured plasma glucose & triglyceride levels (every 60 mins) and glucose concentrations determined from continuous glucose monitoring (CGMS).


Ages Eligible for Study:   45 Years to 65 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patients with Type 2 Diabetes

Inclusion Criteria:

  1. Diet controlled Diabetes
  2. Overweight (BMI > 27 kg/m2 but <50 kg/m2)

Exclusion Criteria:

  1. Hypoglycaemic Agents
  2. Lipid Lowering Agents
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00666861

Australia, Victoria
Alfred Hospital
Melbourne, Victoria, Australia, 3004
Sponsors and Collaborators
Bayside Health
International Diabetes Institute, Australia
Baker Heart Research Institute
Principal Investigator: Bronwyn A Kingwell, PhD Baker Heart Research Institute
  More Information

Responsible Party: Assoc/Prof Bronwyn Kingwell - Executive Director Science Policy and Head, Clinical Physiology, Baker Heart Research Institute Identifier: NCT00666861     History of Changes
Other Study ID Numbers: 290/07
Study First Received: April 23, 2008
Last Updated: July 28, 2009

Additional relevant MeSH terms:
Diabetes Mellitus, Type 2
Diabetes Mellitus
Glucose Metabolism Disorders
Metabolic Diseases
Endocrine System Diseases processed this record on March 27, 2017