Type 2 Diabetes and Exercise - A Pilot Study
|ClinicalTrials.gov Identifier: NCT00666861|
Recruitment Status : Terminated (Pilot study superseded by a larger NHMRC funded trial)
First Posted : April 25, 2008
Last Update Posted : July 30, 2009
A randomised, cross-over trial targeting a small sample of older (age 45-65 years) overweight adults with type 2 diabetes the aims of this pilot study are to:
- Determine the feasibility of investigating the acute effects of prolonged sedentary behaviour (sitting) in this target group.
- Compare the acute effects of a single prolonged (8 hour) bout of sedentary behaviour (sitting) on glucose and triglyceride concentrations and key muscle and adipose regulatory enzymes to a similar bout of sedentary behaviour combined with intermittent bouts of light-intensity activity.
|Condition or disease|
|Type 2 Diabetes|
The proposed study will involve a randomised cross-over experimental trial conducted in the laboratory setting in older overweight adults with type 2 diabetes. Participants will receive both of the acute testing conditions in a randomised manner.
Study design: Randomised cross-over pilot trial of 20 overweight/obese older adults with diet-controlled type 2 diabetes involving 2 acute treatment conditions, with a one-week wash-out period between testing conditions (Figure 1 a).
Setting: Acute, supervised laboratory setting within the Alfred and Baker Heart Institute Medical Unit.
Outcomes: We will measure acute responses in laboratory-measured plasma glucose & triglyceride levels (every 60 mins) and glucose concentrations determined from continuous glucose monitoring (CGMS).
|Study Type :||Observational|
|Actual Enrollment :||2 participants|
|Official Title:||Understanding the Acute Effects of Prolonged Sedentary Behaviour (Sitting) on Post-meal Glucose and Lipids - A Pilot Study|
|Study Start Date :||April 2008|
|Actual Primary Completion Date :||October 2008|
|Actual Study Completion Date :||November 2008|
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00666861
|Melbourne, Victoria, Australia, 3004|
|Principal Investigator:||Bronwyn A Kingwell, PhD||Baker Heart Research Institute|