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Effects of Xoçai Antioxidant Supplements on Atherosclerosis Risk Factors

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ClinicalTrials.gov Identifier: NCT00666250
Recruitment Status : Completed
First Posted : April 24, 2008
Last Update Posted : February 8, 2016
Sponsor:
Information provided by (Responsible Party):
University of Utah

Brief Summary:
An antioxidant dietary supplement made from cocoa powder, and extracts of acai, grape and blueberry will be tested for effects on blood sugar, blood pressure, cholesterol and related parameters in human subjects.

Condition or disease Intervention/treatment Phase
Hypertension Dyslipidemia Hyperglycemia Dietary Supplement: Xocai Activ drink Not Applicable

  Show Detailed Description

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 10 participants
Allocation: Non-Randomized
Intervention Model: Crossover Assignment
Masking: Single (Investigator)
Primary Purpose: Prevention
Official Title: Effects of Xoçai Antioxidant Supplements on Atherosclerosis Risk Factors
Study Start Date : January 2006
Actual Primary Completion Date : April 2008
Actual Study Completion Date : April 2008

Resource links provided by the National Library of Medicine


Arm Intervention/treatment
No Intervention: Baseline
Baseline values off chocolate supplement
Experimental: Low Dose
Low dose of dietary supplement 30 ml tid (Activ Xocai Drink)
Dietary Supplement: Xocai Activ drink
proprietary blend of cocoa powder and extracts of acai, grape and blueberry
Other Names:
  • Xocai Activ drink;
  • cocoa powder,
  • acai extract,
  • grape extract,
  • blueberry extract

Experimental: High-dose
High dose of dietary supplement 90 ml tid (Xocai Activ drink)
Dietary Supplement: Xocai Activ drink
proprietary blend of cocoa powder and extracts of acai, grape and blueberry
Other Names:
  • Xocai Activ drink;
  • cocoa powder,
  • acai extract,
  • grape extract,
  • blueberry extract




Primary Outcome Measures :
  1. Blood pressure [ Time Frame: 4 weeks ]

Secondary Outcome Measures :
  1. Plasma Lipids [ Time Frame: 4 weeks ]
  2. Arterial Compliance [ Time Frame: 4 weeks ]
  3. Fasting and post-challenge glucose and insulin [ Time Frame: 4 weeks ]
  4. urine microalbumin/creatinine ratio [ Time Frame: 4 weeks ]


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Ages Eligible for Study:   18 Years to 95 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • healthy adult not taking cocoa supplements

Exclusion Criteria:

  • diabetes mellitus

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00666250


Locations
United States, Utah
Cardiovascular Genetics, University of Utah
Salt Lake City, Utah, United States, 84108
Sponsors and Collaborators
University of Utah
Investigators
Principal Investigator: Eliot Brinton, MD University of Utah

Additional Information:
Responsible Party: University of Utah
ClinicalTrials.gov Identifier: NCT00666250     History of Changes
Other Study ID Numbers: Xocai01
First Posted: April 24, 2008    Key Record Dates
Last Update Posted: February 8, 2016
Last Verified: April 2008

Keywords provided by University of Utah:
blood pressure
dyslipidemia
hyperglycemia

Additional relevant MeSH terms:
Atherosclerosis
Dyslipidemias
Hyperglycemia
Arteriosclerosis
Arterial Occlusive Diseases
Vascular Diseases
Cardiovascular Diseases
Lipid Metabolism Disorders
Metabolic Diseases
Glucose Metabolism Disorders
Antioxidants
Molecular Mechanisms of Pharmacological Action
Protective Agents
Physiological Effects of Drugs