Morphometric Analysis of Orbital Structures in Graves´ Orbitopathy
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT00665795|
Recruitment Status : Completed
First Posted : April 24, 2008
Last Update Posted : November 19, 2013
The purpose of this protocol is to study orbital structures in Graves´ Disease using multidetector computed tomography and color doppler imaging.
Some changes in orbital structures detected by imaging exams could predict severity of the ocular Graves´disease. Thus the study could be useful in improve medical management of patients with Graves´ Disease.
|Condition or disease|
Morphometric analysis of orbital structures in Graves´ Orbitopathy using multidetector computed tomography scan and color doppler imaging:
Patients with Graves´ orbitopathy are evaluated by a complete ophthalmic examination.A prospective study with Multidetector CT scan and Color Doppler of these patients are made to develop parameters capable to predict Dysthyroid Optic Neuropathy (DON).
|Study Type :||Observational|
|Actual Enrollment :||80 participants|
|Official Title:||Morphometric Analysis of Orbital Structures in Graves´ Orbitopathy Using Multidetector Computed Tomography Scan and Color Doppler Imaging.|
|Study Start Date :||July 2005|
|Primary Completion Date :||November 2013|
|Study Completion Date :||November 2013|
1Patients with Graves´orbitophathy.
Patients with Graves´orbitophathy.
2 Patients with detected DON
Patients with Graves´orbitophaty and detected dysthyroid optic neuropathy (DON)
- screening indexes for dysthyroid optic neuropathy [ Time Frame: indexes above 60% of orbital apex crowding were high suspected for DON ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00665795
|General Hospital - University of Sao Paulo - School of Medicine|
|São Paulo, Brazil, 05409 000|
|Study Chair:||Mario L Monteiro, MD, PhD||University of Sao Paulo - School of Medicine|