Joint Stiffness Following Knee Replacement Surgery
Our primary research question is to find out whether there is a genetic component to the development of joint contractures following knee surgery, through the application of lab techniques.
|Study Design:||Observational Model: Case Control
Time Perspective: Retrospective
|Official Title:||Capsular Changes in Joint Contractures Post-Knee Arthroplasty:A Case-Control Study|
- Gene expression [ Time Frame: Dec 2015 ] [ Designated as safety issue: No ]
|Study Start Date:||December 2006|
|Study Completion Date:||April 2015|
|Primary Completion Date:||April 2015 (Final data collection date for primary outcome measure)|
After total knee replacement surgery, some people develop joint stiffness, which is also called a joint contracture. Contractures cause the envelope of the knee (called the capsule) to stiffen and become rigid so the patient can no longer move their knee the way they used to. After stretching and other exercises, only a surgery can try and divide or remove the contracture. The main purpose of this research is to study the cause of the contracture and specifically if certain people are predisposed to contractures.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00664651
|Ottawa Hospital Research Institute|
|Ottawa, Ontario, Canada, K1Y 4E9|
|Principal Investigator:||Guy Trudel, MD,MSc,FRCPC||OHRI / The Ottawa Hospital|