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Intensive Meditation and Migraines: Effects on Health and Well Being

This study has been completed.
Information provided by (Responsible Party):
Madhav Goyal, Johns Hopkins University Identifier:
First received: April 21, 2008
Last updated: July 28, 2016
Last verified: July 2016
Participants completing training in intensive meditation and continuing frequent practice for one year would experience reduced frequency, duration and severity of headaches along with improved awareness of the triggers of their symptoms, improved quality of life and mental health, improved heart rate variability, and reduced inflammation.

Condition Intervention
Chronic Daily Headache
Behavioral: Vipassana Meditation

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Intensive Meditation and Migraines: Effects on Health and Well Being

Resource links provided by NLM:

Further study details as provided by Johns Hopkins University:

Primary Outcome Measures:
  • number of migraine days, number of headache days [ Time Frame: 3,6,12 months ]

Secondary Outcome Measures:
  • severity of headaches [ Time Frame: 3,6,12 months ]
  • quality of life [ Time Frame: 3,6,12 months ]
  • Heart Rate Variability [ Time Frame: 3,6,12 months ]

Enrollment: 36
Study Start Date: April 2008
Study Completion Date: June 2014
Primary Completion Date: February 2014 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: 1
Structured Intervention Group
Behavioral: Vipassana Meditation
12 day retreat where participants learn to meditate
Active Comparator: 2.Comparison group
Unstructured comparison group
Behavioral: Vipassana Meditation
12 day retreat where participants learn to meditate


Ages Eligible for Study:   18 Years to 75 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Chronic Daily Headache, defined as a headache at least 15 days of the month, of which at least 8 are migraines.

Exclusion Criteria:1.

  • Severe depression, anxiety, panic attacks, psychosis or dementia that may interfere with ability to participate in a 10 day course
  • Active alcoholism on screening or use of illicit drugs within the last 3 months
  • Already completed a 10 day course
  • Actively involved in another form of meditation over the past 6 months
  • Women who are pregnant, planning pregnancy during trial period, or lactating.
  Contacts and Locations
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Please refer to this study by its identifier: NCT00663585

United States, Maryland
Johns Hopkins School of Medicine
Baltimore, Maryland, United States, 21287
Sponsors and Collaborators
Johns Hopkins University
Study Director: Madhav Goyal, MD, MPH Johns Hopkins University
  More Information

Responsible Party: Madhav Goyal, Assistant Professor, Johns Hopkins University Identifier: NCT00663585     History of Changes
Other Study ID Numbers: NA_00016428
Study First Received: April 21, 2008
Last Updated: July 28, 2016

Keywords provided by Johns Hopkins University:

Additional relevant MeSH terms:
Migraine Disorders
Headache Disorders
Headache Disorders, Primary
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Neurologic Manifestations
Signs and Symptoms processed this record on May 22, 2017