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Functional Tests in Individuals With Chronic Obstructive Pulmonary Disease (COPD)

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00660738
First Posted: April 17, 2008
Last Update Posted: January 24, 2012
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Collaborator:
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.
Information provided by (Responsible Party):
Bruna Varanda Pessoa, Universidade Federal de Sao Carlos
  Purpose
Objectives: to evaluate and compare the responses to the various functional tests, and the concordance between the six-minute walk test in hallway (6MWT) and the of oval track (6MWToT), of treadmill (6MWTT), and of treadmill with inclination (6MWTTI), the six-minute step test (6MST) and the sit-to-stand test (STST), in patients with Chronic Obstructive Pulmonary Disease (COPD), and to correlate the responses with functional state and quality of life. Methods: Ten patients with COPD (71±8years, FEV1<80%predicted) were assessed using the functional tests. A dyspnea was assessed using the London Chest Activity of Daily Living and the Medical Research Council scales; and the quality of life was assessed using the St George's Respiratory Questionnaire (SGRQ).

Condition
Chronic Obstructive Pulmonary Disease

Study Type: Observational
Study Design: Observational Model: Case-Crossover
Time Perspective: Prospective
Official Title: Comparison of Different Functional Tests and Relation With Functional State and Quality of Life in Individuals With Chronic Obstructive Pulmonary Disease (COPD)

Resource links provided by NLM:


Further study details as provided by Bruna Varanda Pessoa, Universidade Federal de Sao Carlos:

Enrollment: 11
Study Start Date: January 2007
Study Completion Date: February 2008
Primary Completion Date: February 2008 (Final data collection date for primary outcome measure)
Groups/Cohorts
01
Patients with clinical and spirometric diagnosis of COPD, with FEV1<80%

Detailed Description:
Results: In the interests analysis, there was lower walking distance in the 6MWTT and 6MWTTI was observed, to compare in the 6MWT and 6MWToT; the ΔSp,O2 (delta of arterial oxygen saturation measured by pulse oximeter) in the 6MWTTI was significantly greater that in the 6MWT, but not between to change in dyspnea and fatigue/pain in the lower-limbs between rest and exercise of peak (Δ). Concordance and correlation was observed between the lower Sp,O2 of the 6MWT with the 6MWToT, 6MWTT, 6MWTTI, 6MST and STST. Strong correlations was observed between the performances on the 6MST and 6MWT, 6MWToT and 6MWTT; and between the physical activity domain of the SGRQ with the performances in the 6MWT, 6MWToT, 6MWTT,6MST and STST. Conclusion: The functional tests produced similar subjective responses; however, the 6MWTTI caused greater desaturation that 6MWT. The concordance between the 6MWT and the tests performed, suggests acceptable use of any these tests in the physiotherapeutic clinical routine of the individuals COPD. The tests in performed, except the 6MWTTI, shown to be indicators of the quality of life (physical activity domain).
  Eligibility

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Ages Eligible for Study:   55 Years to 81 Years   (Adult, Senior)
Sexes Eligible for Study:   Male
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
chronic obstructive pulmonary disease.
Criteria

Inclusion Criteria:

  • Tiffeneau index<70% e 30%<FEV1<80% predict;
  • no presenting exacerbation during the study period;
  • clinical stability for the four weeks preceding the study outset;
  • no-smokers or ex-smokers.

Exclusion Criteria:

  • being incapable of understanding the scales and questionary;
  • being unable to perform the tests.
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00660738


Locations
Brazil
Special Unit of Respiratory Physiotherapy of Federal University of Sao Carlos (UFSCar)
São Carlos, São Paulo, Brazil, 676
Sponsors and Collaborators
Universidade Federal de Sao Carlos
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.
Investigators
Principal Investigator: Bruna Varanda Pessoa, Master, Physiotherapist Universidade Federal de Sao Carlos
  More Information

Publications:

Responsible Party: Bruna Varanda Pessoa, Master Degree, Universidade Federal de Sao Carlos
ClinicalTrials.gov Identifier: NCT00660738     History of Changes
Other Study ID Numbers: 074/2007
First Submitted: April 10, 2008
First Posted: April 17, 2008
Last Update Posted: January 24, 2012
Last Verified: January 2012

Keywords provided by Bruna Varanda Pessoa, Universidade Federal de Sao Carlos:
chronic obstructive pulmonary disease
walking
exercise test
quality of life
dyspnea
desaturation

Additional relevant MeSH terms:
Lung Diseases
Lung Diseases, Obstructive
Pulmonary Disease, Chronic Obstructive
Respiratory Tract Diseases