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Effective High Aerobic Intensity Endurance Training Regimes in Chronic Obstructive Pulmonary Disease (COPD) Patients

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00658853
First Posted: April 15, 2008
Last Update Posted: July 18, 2016
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
Norwegian University of Science and Technology
  Purpose
4 times 4 minutes interval training with and without hyperoxia is more effective than low intensity endurance training.

Condition Intervention
Pulmonary Disease, Chronic Obstructive Hyperoxia Behavioral: 4 times 4 minutes high aerobic intensity one leg cycling

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Effective High Aerobic Intensity Interval Training to Improve Maximal Oxygen Uptake in COPD Patients

Resource links provided by NLM:


Further study details as provided by Norwegian University of Science and Technology:

Primary Outcome Measures:
  • VO2peak [ Time Frame: 10 weeks ]
  • Ventilation [ Time Frame: 10 weeks ]
  • FEV1 [ Time Frame: 10 weeks ]
  • Walking performance [ Time Frame: 10 weeks ]

Secondary Outcome Measures:
  • Quality of life [ Time Frame: 3 months ]
  • SPSS [ Time Frame: 3 months ]

Enrollment: 26
Study Start Date: January 2004
Study Completion Date: February 2006
Primary Completion Date: February 2006 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Active Comparator: 1
High aerobic intensity treadmill walking. 4 by 4 minutes interval training on a 5% graded treadmill at a heart rate corresponding to 85-95% of maximal heart rate. 3 times per week for 10 weeks.
Behavioral: 4 times 4 minutes high aerobic intensity one leg cycling
3 times per week for 10 weeks
Active Comparator: 2
4 times 4 minutes interval training in hyperoxia - 100% oxygen
Behavioral: 4 times 4 minutes high aerobic intensity one leg cycling
3 times per week for 10 weeks
Active Comparator: 3
One leg at a time training 4 times 4 minutes interval training using cycling ergometer
Behavioral: 4 times 4 minutes high aerobic intensity one leg cycling
3 times per week for 10 weeks

  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   20 Years to 85 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • COPD

Exclusion Criteria:

  • Heart disease
  • Walking or cycling inabilities
  • Other diseases
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00658853


Locations
Norway
Norwegian University of Science and Technology
Trondheim, Norway, NO-7489
Sponsors and Collaborators
Norwegian University of Science and Technology
Investigators
Principal Investigator: Jan Helgerud, PhD Norwegian University of Science and Technology
  More Information

Publications:
Responsible Party: Norwegian University of Science and Technology
ClinicalTrials.gov Identifier: NCT00658853     History of Changes
Other Study ID Numbers: 149-03
First Submitted: April 10, 2008
First Posted: April 15, 2008
Last Update Posted: July 18, 2016
Last Verified: July 2016

Keywords provided by Norwegian University of Science and Technology:
COPD
training
VO2peak
performance
ventilation
high aerobic intensity treadmill walking
one leg training by cycling

Additional relevant MeSH terms:
Lung Diseases
Pulmonary Disease, Chronic Obstructive
Chronic Disease
Hyperoxia
Respiratory Tract Diseases
Lung Diseases, Obstructive
Disease Attributes
Pathologic Processes
Signs and Symptoms, Respiratory
Signs and Symptoms