Rehabilitation Program for Cognitive Deficits in Ugandan Children After Cerebral Malaria
|ClinicalTrials.gov Identifier: NCT00658450|
Recruitment Status : Completed
First Posted : April 15, 2008
Last Update Posted : December 6, 2012
|Condition or disease||Intervention/treatment|
|Malaria, Cerebral||Behavioral: Cognitive rehabilitation training|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||123 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||None (Open Label)|
|Official Title:||A Randomised Trial to Investigate the Effect of a Rehabilitation Program for Cognitive Deficits in Ugandan Children After Cerebral Malaria.|
|Study Start Date :||February 2008|
|Primary Completion Date :||October 2010|
|Study Completion Date :||October 2010|
Experimental: Cognitive rehabilitation training
Children in this arm will the receive the intervention comprising of 16 cognitive rehabilitation training (CRT) exercises for 8 weeks. These exercises will train different cognitive skills including attention, visual spatial processing, logical skills and memory.
Behavioral: Cognitive rehabilitation training
A computerised cognitive training package where children will be required to complete several cognitive tasks. The aim is to strengthen the different cognitive processes during these tasks which in turn may lead to improve cognitive processes.
Children will complete these tasks in 16 session for 8 weeks.
Other Name: Intervention group
No Intervention: Treatment as usual
Children in this group will not receive any intervention, they will undergo the usual post discharge treatment for brain injured children at Mulago Hospital (the study site). This is the treatment as usual (TAU) group.
- Improvement in attention scores [ Time Frame: 6 months ]
- Improvement in memory, reasoning, planning, behaviour and academic achievement [ Time Frame: 6 months ]
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00658450
|Mulago hospital Acute Care Unit and the Cerebral Malaria Project|
|Kampala, Uganda, 7051|
|Study Chair:||Charles Ibingira, MMED||Chairman, Makerere University Faculty of Medicine Research and Ethics Committee|