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Retrospective Postoperative ARDS Study at Vanderbilt University

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00656071
First Posted: April 10, 2008
Last Update Posted: September 7, 2012
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
Christopher Hughes, Vanderbilt University
  Purpose
By examining the intraoperative anesthetic characteristics of patients who developed ARDS postoperatively, we hope to identify variables which have a positive or negative association on the development of ARDS.

Condition
ARDS

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Retrospective
Official Title: Intraoperative Anesthetic Characteristics and the Development of ARDS

Resource links provided by NLM:


Further study details as provided by Christopher Hughes, Vanderbilt University:

Primary Outcome Measures:
  • ARDS [ Time Frame: data pulled from 10/2000 - 08/2007 ]

Enrollment: 89
Study Start Date: October 2007
Study Completion Date: August 2008
Primary Completion Date: August 2008 (Final data collection date for primary outcome measure)
Groups/Cohorts
1
Control -- postoperative mechanical ventilation patients without ARDS
2
Cases -- postoperative mechanical ventilation patients with ARDS

Detailed Description:
Acute respiratory distress syndrome (ARDS) is a pulmonary disease process that affects post-surgical patients in the intensive care unit and leads to significant patient morbidity and mortality and hospital cost. Extensive research has been conducted in the diagnosis and treatment of ARDS. To date, however, very little research examining the effect of the operative course on the development of ARDS has been reported. By examining the intraoperative anesthetic characteristics of patients who developed ARDS postoperatively, we hope to identify variables which have a positive or negative association on the development of ARDS. Once identified, the variables can be confirmed by future studies and encourage change in clinical care to decrease the occurrence of ARDS in surgical patients.
  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   11 Years and older   (Child, Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
The surgical and post-op patients at VUMC. The collection dates will be from October 1, 2001 until August 31, 2007.
Criteria

Inclusion Criteria:

  • ARDS
  • post-surgical
  • ventilator

Exclusion Criteria:

  • rib fracture
  • pneumonia
  • sepsis
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00656071


Locations
United States, Tennessee
Vanderbilt University Medical Center
Nashville, Tennessee, United States, 37212
Sponsors and Collaborators
Vanderbilt University
Investigators
Principal Investigator: Christopher G Hughes, M.D. Vanderbilt University Medical Center
  More Information

Additional Information:
Responsible Party: Christopher Hughes, Assistant Professor, Vanderbilt University
ClinicalTrials.gov Identifier: NCT00656071     History of Changes
Other Study ID Numbers: CHughes-PGY2
First Submitted: April 4, 2008
First Posted: April 10, 2008
Last Update Posted: September 7, 2012
Last Verified: September 2012

Keywords provided by Christopher Hughes, Vanderbilt University:
ARDS
Acute respiratory distress syndrome
Adult respiratory distress syndrome
respiratory distress