Expanded Access Study of RAD001 in Metastatic Renal Cell Cancer Patients Who Are Intolerant of or Who Have Failed Despite Prior Vascular Endothelial Growth Factor Therapy
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An Open-Label, Multi-Center, Expanded Access Study of RAD001 in Patients With Metastatic Carcinoma of the Kidney Who Are Intolerant of or Have Progressed Despite Any AvailableVascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitor Therapy
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Ages Eligible for Study:
18 Years and older (Adult, Senior)
Sexes Eligible for Study:
≥ 18 years old; metastatic renal cancer, intolerant of or failed sunitinib and/or sorafenib
Adequate bone marrow function, liver function, renal function
Adequate birth control
Previously received RAD001 or other mTOR inhibitors, known hypersensitivity to rapamycin, chronic systemic treatment with corticosteroids or immunosuppressive agents (prednisone ≤ 20 mg/day for adrenal insufficiency OK
Keywords provided by Novartis ( Novartis Pharmaceuticals ):
metastatic renal cell cancer
progression despite VEGF receptors
Additional relevant MeSH terms:
Carcinoma, Renal Cell
Neoplasms, Glandular and Epithelial
Neoplasms by Histologic Type
Neoplasms by Site