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Mitral Valve Area Assessment: Comparison With Transthoracic Echocardiography and Magnetic Resonance Imaging

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ClinicalTrials.gov Identifier: NCT00654472
Recruitment Status : Unknown
Verified April 2008 by Florence Nightingale Hospital, Istanbul.
Recruitment status was:  Recruiting
First Posted : April 8, 2008
Last Update Posted : April 8, 2008
Sponsor:
Information provided by:
Florence Nightingale Hospital, Istanbul

Brief Summary:
To compare mitral valve area in rheumatic mitral valve stenosis with cardiac magnetic resonance imaging and conventional transthoracic echocardiography.

Condition or disease
Mitral Valve Stenosis

Detailed Description:
Clinical assessment of severity of mitral stenosis depends on both the presence of symptoms and mitral valve area . Evaluation of mitral valve area with transthoracic echocardiography maintains rapid, accurate analysis of valve disease and serves as a practical gold standard for clinical evaluation. Cardiac magnetic resonance imaging (CMRI) is a recently used method that allows to evaluate cardiac structures and function noninvasively. Direct visualization of valve area with CMRI is also possible and it has been shown that the valve area assessed by CMRI planimetry correlates reliably with the invasive assessment. Velocity-encoded cardiac magnetic resonance imaging can be used to quantify mitral valve area. The objective of this study was to evaluate mitral valve area with CMRI and compare it with echocardiographic methods including 2D planimetry, Doppler continuation equation and Doppler pressure half-time

Study Type : Observational
Estimated Enrollment : 30 participants
Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Quantification of Rheumatic Mitral Stenosis With Cardiac Magnetic Resonance Imaging and Comparison With Transthoracic Echocardiography
Study Start Date : April 2008
Estimated Primary Completion Date : June 2008
Estimated Study Completion Date : June 2008

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Group/Cohort
A
Mitral valve area above 1.5 cm2
B
Mitral valve area 1.5 cm2 and below 1.5 cm2




Information from the National Library of Medicine

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Ages Eligible for Study:   20 Years to 65 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
tertiary care clinic
Criteria

Inclusion Criteria:

  • rheumatic mitral valve stenosis

Exclusion Criteria:

  • Degenerative mitral valve disease
  • EF<50%
  • atrial fibrillation
  • inconclusive planimetric assessment
  • moderate or severe mitral regurgitation
  • moderate or severe aortic regurgitation
  • history of previous mitral valve commissurotomy or balloon valvotomy

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00654472


Contacts
Contact: Saide Aytekin, Professor 00902122244950 ext 4038 saideaytekin@gmail.com
Contact: Özlem Yıldırımtürk, Professor 00902122244950 ext 4020 ozlemyt@gmail.com

Locations
Turkey
Florence Nightinngale Hospital Recruiting
Istanbul, Turkey, 34381
Contact: Saide Ayetkin, Professor    00902122244950 ext 4038    saideaytekin@gmail.com   
Contact: Özlem Yıldırımtürk, MD    00902122244950 ext 4020    ozlemyt@gmail.com   
TC.Istanbul Bilim University, Florence Nightingale Hospital, Division of Cardiology Recruiting
Istanbul, Turkey, 34381
Contact: Saide Aytekin, Professor    00902122244950 ext 4038    saideaytekin@gmail.com   
Sub-Investigator: Özlem Yıldırımtürk, MD         
Principal Investigator: Saide Aytekin, Professor         
Sub-Investigator: Aylin Tuğcu, MD         
Sub-Investigator: Yelda Tayyareci, MD         
Sub-Investigator: Onur Levent Ulusoy, MD         
Sub-Investigator: Cihan Duran, MD         
Sub-Investigator: Mustafa Şirvancı, MD         
Sponsors and Collaborators
Florence Nightingale Hospital, Istanbul
Investigators
Study Director: Saide Aytekin, Professor T.C. Istanbul Bilim University, Florence Nightingale Hospital, Division of Cardiology

Publications:
Responsible Party: Prof. Dr. Saide Aytekin, T.C. Istanbul Bilim University, Florence Nightingale Hospital
ClinicalTrials.gov Identifier: NCT00654472     History of Changes
Other Study ID Numbers: OY1975
First Posted: April 8, 2008    Key Record Dates
Last Update Posted: April 8, 2008
Last Verified: April 2008

Keywords provided by Florence Nightingale Hospital, Istanbul:
magnetic resonance imaging, mitral valve area

Additional relevant MeSH terms:
Constriction, Pathologic
Mitral Valve Stenosis
Pathological Conditions, Anatomical
Heart Valve Diseases
Heart Diseases
Cardiovascular Diseases