Mitral Valve Area Assessment: Comparison With Transthoracic Echocardiography and Magnetic Resonance Imaging

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified April 2008 by Florence Nightingale Hospital, Istanbul.
Recruitment status was:  Recruiting
Sponsor:
Information provided by:
Florence Nightingale Hospital, Istanbul
ClinicalTrials.gov Identifier:
NCT00654472
First received: April 2, 2008
Last updated: April 7, 2008
Last verified: April 2008
  Purpose
To compare mitral valve area in rheumatic mitral valve stenosis with cardiac magnetic resonance imaging and conventional transthoracic echocardiography.

Condition
Mitral Valve Stenosis

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Quantification of Rheumatic Mitral Stenosis With Cardiac Magnetic Resonance Imaging and Comparison With Transthoracic Echocardiography

Resource links provided by NLM:


Further study details as provided by Florence Nightingale Hospital, Istanbul:

Estimated Enrollment: 30
Study Start Date: April 2008
Estimated Study Completion Date: June 2008
Estimated Primary Completion Date: June 2008 (Final data collection date for primary outcome measure)
Groups/Cohorts
A
Mitral valve area above 1.5 cm2
B
Mitral valve area 1.5 cm2 and below 1.5 cm2

Detailed Description:
Clinical assessment of severity of mitral stenosis depends on both the presence of symptoms and mitral valve area . Evaluation of mitral valve area with transthoracic echocardiography maintains rapid, accurate analysis of valve disease and serves as a practical gold standard for clinical evaluation. Cardiac magnetic resonance imaging (CMRI) is a recently used method that allows to evaluate cardiac structures and function noninvasively. Direct visualization of valve area with CMRI is also possible and it has been shown that the valve area assessed by CMRI planimetry correlates reliably with the invasive assessment. Velocity-encoded cardiac magnetic resonance imaging can be used to quantify mitral valve area. The objective of this study was to evaluate mitral valve area with CMRI and compare it with echocardiographic methods including 2D planimetry, Doppler continuation equation and Doppler pressure half-time
  Eligibility

Ages Eligible for Study:   20 Years to 65 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
tertiary care clinic
Criteria

Inclusion Criteria:

  • rheumatic mitral valve stenosis

Exclusion Criteria:

  • Degenerative mitral valve disease
  • EF<50%
  • atrial fibrillation
  • inconclusive planimetric assessment
  • moderate or severe mitral regurgitation
  • moderate or severe aortic regurgitation
  • history of previous mitral valve commissurotomy or balloon valvotomy
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00654472

Locations
Turkey
Florence Nightinngale Hospital
Istanbul, Turkey, 34381
TC.Istanbul Bilim University, Florence Nightingale Hospital, Division of Cardiology
Istanbul, Turkey, 34381
Sponsors and Collaborators
Florence Nightingale Hospital, Istanbul
Investigators
Study Director: Saide Aytekin, Professor T.C. Istanbul Bilim University, Florence Nightingale Hospital, Division of Cardiology
  More Information

Publications:
Responsible Party: Prof. Dr. Saide Aytekin, T.C. Istanbul Bilim University, Florence Nightingale Hospital
ClinicalTrials.gov Identifier: NCT00654472     History of Changes
Other Study ID Numbers: OY1975 
Study First Received: April 2, 2008
Last Updated: April 7, 2008

Keywords provided by Florence Nightingale Hospital, Istanbul:
magnetic resonance imaging, mitral valve area

Additional relevant MeSH terms:
Constriction, Pathologic
Mitral Valve Stenosis
Pathological Conditions, Anatomical
Heart Valve Diseases
Heart Diseases
Cardiovascular Diseases

ClinicalTrials.gov processed this record on January 19, 2017