Exercise and Muscle Protein Signalling

This study has been withdrawn prior to enrollment.
(A paper on the same topic came out just before we wanted to start our study.)
Information provided by (Responsible Party):
Milou Beelen, Maastricht University Medical Center
ClinicalTrials.gov Identifier:
First received: April 1, 2008
Last updated: April 13, 2015
Last verified: April 2015
This study examines the muscle protein signalling response after resistance and endurance exercise. We hypothesize that the signalling response after endurance and resistance exercise will be partly similar.

Condition Intervention
Muscle Protein Synthesis
Other: exercise

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Open Label
Primary Purpose: Basic Science
Official Title: The Impact of Resistance Versus Endurance Exercise on the Muscle Protein Signalling Response

Resource links provided by NLM:

Further study details as provided by Maastricht University Medical Center:

Primary Outcome Measures:
  • The difference in phosphorylation of different signalling proteins in the cascade towards protein synthesis [ Time Frame: 1 day ] [ Designated as safety issue: No ]

Enrollment: 0
Study Start Date: September 2008
Estimated Study Completion Date: February 2009
Estimated Primary Completion Date: February 2009 (Final data collection date for primary outcome measure)
Intervention Details:
    Other: exercise
    1 hour of endurance or resistance exercise

Ages Eligible for Study:   18 Years to 28 Years
Genders Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • healthy men
  • inactive

Exclusion Criteria:

  • enrolled in a endurance and/or resistance training program
  Contacts and Locations
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Please refer to this study by its ClinicalTrials.gov identifier: NCT00653679

Maastricht University
Maastricht, Limburg, Netherlands, 6200 MD
Sponsors and Collaborators
Maastricht University Medical Center
Principal Investigator: L.J.C van Loon, PhD Maastricht University
  More Information

Responsible Party: Milou Beelen, Dr., Maastricht University Medical Center
ClinicalTrials.gov Identifier: NCT00653679     History of Changes
Other Study ID Numbers: MEC0001 
Study First Received: April 1, 2008
Last Updated: April 13, 2015
Health Authority: Netherlands: The Central Committee on Research Involving Human Subjects (CCMO)

Keywords provided by Maastricht University Medical Center:
muscle protein signalling
protein synthesis

ClinicalTrials.gov processed this record on May 30, 2016