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Exercise and Muscle Protein Signalling

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ClinicalTrials.gov Identifier: NCT00653679
Recruitment Status : Withdrawn (A paper on the same topic came out just before we wanted to start our study.)
First Posted : April 7, 2008
Last Update Posted : April 14, 2015
Information provided by (Responsible Party):
Milou Beelen, Maastricht University Medical Center

Brief Summary:
This study examines the muscle protein signalling response after resistance and endurance exercise. We hypothesize that the signalling response after endurance and resistance exercise will be partly similar.

Condition or disease Intervention/treatment
Muscle Protein Synthesis Other: exercise

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 0 participants
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: None (Open Label)
Primary Purpose: Basic Science
Official Title: The Impact of Resistance Versus Endurance Exercise on the Muscle Protein Signalling Response
Study Start Date : September 2008
Estimated Primary Completion Date : February 2009
Estimated Study Completion Date : February 2009

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Intervention Details:
    Other: exercise
    1 hour of endurance or resistance exercise

Primary Outcome Measures :
  1. The difference in phosphorylation of different signalling proteins in the cascade towards protein synthesis [ Time Frame: 1 day ]

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 28 Years   (Adult)
Sexes Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • healthy men
  • inactive

Exclusion Criteria:

  • enrolled in a endurance and/or resistance training program

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00653679

Maastricht University
Maastricht, Limburg, Netherlands, 6200 MD
Sponsors and Collaborators
Maastricht University Medical Center
Principal Investigator: L.J.C van Loon, PhD Maastricht University

Responsible Party: Milou Beelen, Dr., Maastricht University Medical Center
ClinicalTrials.gov Identifier: NCT00653679     History of Changes
Other Study ID Numbers: MEC0001
First Posted: April 7, 2008    Key Record Dates
Last Update Posted: April 14, 2015
Last Verified: April 2015

Keywords provided by Milou Beelen, Maastricht University Medical Center:
muscle protein signalling
protein synthesis