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Metabolic Syndrome and Leptin Level Associated With Fructose Consumption in Spain

This study has been completed.
Information provided by:
Hospital Mateo Orfila Identifier:
First received: March 28, 2008
Last updated: August 3, 2009
Last verified: August 2009
A Food Frequency Questionnaire (FFQ), will be provided to 800 adults to assess overall fructose intake and this will be related to a number of features related to the metabolic syndrome, including serum leptin, characteristic features of metabolic syndrome (body mass index, waist circumference, plasma lipids, blood pressure, HOMA index,fasting glucose and fasting insulin levels) and other as: CRP, fibrinogen, homocysteine and uric acid.


Study Type: Observational
Study Design: Observational Model: Ecologic or Community
Time Perspective: Cross-Sectional
Official Title: Prevalence of Cardiovascular Risk Factors in Minorca - Spain

Resource links provided by NLM:

Further study details as provided by Hospital Mateo Orfila:

Primary Outcome Measures:
  • Serum leptin levels as it relates to fructose intake [ Time Frame: Epidemiological association ]

Secondary Outcome Measures:
  • Relationship of metabolic syndrome features with fructose intake. This includes measuring all 5 components of metabolic syndrome, assessing insulin resistance by HOMA, and measuring some markers of inflammation (CRP, fibrinogen, homocysteine) [ Time Frame: Epidemiological ]

Biospecimen Retention:   Samples Without DNA
Serum and urine collections.

Estimated Enrollment: 800
Study Start Date: June 2008
Estimated Study Completion Date: June 2009
Primary Completion Date: January 2009 (Final data collection date for primary outcome measure)

Ages Eligible for Study:   18 Years to 70 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
800 Adults, age 18 to 70

Inclusion Criteria:

  • Adults, 18-70 years of age

Exclusion Criteria:

  • Diabetes
  • Kidney Failure
  • Heart Failure
  • Cancer
  Contacts and Locations
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Please refer to this study by its identifier: NCT00651001

Renal Unit of Mateo Orfila Hospital, Balearic Islands - Spain
Menorca, Balearic Islands, Spain, 07703
Sponsors and Collaborators
Hospital Mateo Orfila
  More Information

Responsible Party: Perez-Pozo, Santos E. Lopez-Lillo, Julian. Johnson, Richard, Hospital Mateo Orfila, University of Florida Identifier: NCT00651001     History of Changes
Other Study ID Numbers: IbSalut-M-002
Study First Received: March 28, 2008
Last Updated: August 3, 2009

Keywords provided by Hospital Mateo Orfila:
metabolic syndrome
blood pressure
Relationship of fructose intake to leptin levels
Relationship of fructose to metabolic syndrome
Relationship of fructose to inflammation parameters
Relationship of fructose to blood pressure

Additional relevant MeSH terms:
Metabolic Syndrome X
Insulin Resistance
Glucose Metabolism Disorders
Metabolic Diseases processed this record on August 18, 2017