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Prospective Assessment in Newborns for Diabetes Autoimmunity (PANDA)

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified May 2011 by Augusta University.
Recruitment status was:  Recruiting
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
University of Florida
Emory University
Medical University of South Carolina
University of South Carolina
Information provided by:
Augusta University Identifier:
First received: March 28, 2008
Last updated: May 12, 2011
Last verified: May 2011
This is an observational study designed to help researchers understand the genetics and pathogenesis of type 1 diabetes, and to identify biomarkers for disease and disease complication prediction.

Type 1 Diabetes

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: 1. Prospective Studies in Infants of the Immunopathogenesis of Type 1 Diabetes 2. Consortium for Identification of Environmental Triggers of Type 1 Diabetes: MCG/UF Clinical Center 3. Identification of Serum Protein Markers for Type 1 Diabetes Using Mass-Spectrometry Techniques 4. Validation of Microarray-Based Biomarkers for Type 1 Diabetes 5. Development of Microarray-Based Biomarkers for Type 1 Diabetes 6. Proteomic Changes/Progression of Human Type 1 Diabetes 7. Identification and Validation of Serum Biomarkers for T1D

Resource links provided by NLM:

Further study details as provided by Augusta University:

Primary Outcome Measures:
  • autoantibodies against the pancreas and type 1 diabetes [ Time Frame: 50 years ]

Secondary Outcome Measures:
  • Risk factors for type 1 diabetes [ Time Frame: 50 years ]

Biospecimen Retention:   Samples With DNA
whole blood, DNA, serum, RNA, urine

Estimated Enrollment: 50000
Study Start Date: July 1997


healthy individuals with no family history of type 1 diabetes



Subjects with islet autoantibodies or high-risk diabetes genes


type 1 diabetes:

subjects with type 1 diabetes

Detailed Description:
This study is designed to identify people who are at risk for developing type 1 diabetes, based on their genetics, family history and autoimmunity status, and to understand the role genetics plays in the development of the complications associated with type 1 diabetes in patients already affected by type 1 diabetes.

Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
newborns, young children, adults with or without type 1 diabetes

Inclusion Criteria: all are welcome -

Exclusion Criteria:

  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00649246

Contact: Diane I Hopkins, MS, CCRC 706-721-4161
Contact: Leigh Steed, RN, CCRA 404-252-0844

United States, Florida
University of Florida Recruiting
Gainesville, Florida, United States, 32608
Contact: Angie Choate, BS    352-334-0843   
Contact: Angela Wilcox, BS    352-334-0843      
Principal Investigator: Desmond Schatz, MD         
United States, South Carolina
Medical University of South Carolina Recruiting
Charleston, South Carolina, United States, 29425
Contact: Lori Spillers, RN    843-792-8166   
Principal Investigator: Louis Luttrel, MD         
University of South Carolina Recruiting
Columbia, South Carolina, United States, 29208
Contact: Joan Thomas    803-251-7870   
Principal Investigator: Elizabeth Mayer-Davis, PhD         
Sponsors and Collaborators
Augusta University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
University of Florida
Emory University
Medical University of South Carolina
University of South Carolina
Principal Investigator: Jin Xiong She, PhD Augusta University
  More Information

Additional Information:
Responsible Party: Jin Xiong She Ph.D., Center for Biotechnology and Genomic Medicine at the Medical College of Georgia Identifier: NCT00649246     History of Changes
Other Study ID Numbers: DK63865 - PANDA
U01DK063865 ( US NIH Grant/Contract Award Number )
Study First Received: March 28, 2008
Last Updated: May 12, 2011

Keywords provided by Augusta University:
type 1 diabetes

Additional relevant MeSH terms:
Diabetes Mellitus
Diabetes Mellitus, Type 1
Autoimmune Diseases
Glucose Metabolism Disorders
Metabolic Diseases
Endocrine System Diseases
Immune System Diseases processed this record on May 25, 2017