Troponin Elevation in the Elderly Patient With Hip Fracture

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00647309
Recruitment Status : Unknown
Verified June 2012 by Dr. Marina Arad, Sheba Medical Center.
Recruitment status was:  Recruiting
First Posted : March 31, 2008
Last Update Posted : June 12, 2012
Information provided by (Responsible Party):
Dr. Marina Arad, Sheba Medical Center

Brief Summary:

Elevated troponin is powerful and independent adverse prognostic marker in patient with ACS. However, non specific (non cardiac) troponin elevation is a common finding among hospitalized patients and worse prognosis too.

The aim of this study is examine the prevalence of incidental cardiac troponin rise in a group of patient aged 65 and over admitted to geriatric department with hip fracture, and influence of troponin elevation on outcomes like ACS, death, motor and cognitive function.

Condition or disease
Hip Fracture

Detailed Description:

data collection will include epidemiological data (age, gender, living arrangement, basic functional status, fracture date, surgery date, surgery type, length of stay) as well as previous comorbidities. in addition, routine blood tests and baseline ECG will be recorded.

troponin levels will be studied within 24 hours from admission, and 24 hours following surgery. in case of elevated troponin levels, ECG will be repeated, and echocardiography together with a cardiologist evaluation will be carried out.

data regarding in-hospital complications, motor and cognitive function (by FIM scale) and lab will be recorded. after discharge. followup will be recorded every 3 months, up to 1 year period, recoding the above mentioned data.

Study Type : Observational
Estimated Enrollment : 100 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Correlation Between Troponin Level and Rehabilitation Outcome in Elderly Patient With Hip Fracture
Study Start Date : April 2008
Estimated Primary Completion Date : February 2013
Estimated Study Completion Date : June 2013

Resource links provided by the National Library of Medicine


Primary Outcome Measures :
  1. all cause mortality, motor and cognitive function [ Time Frame: one year ]

Biospecimen Retention:   Samples With DNA
whole blood

Information from the National Library of Medicine

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Ages Eligible for Study:   65 Years and older   (Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
patients aged 65 years and over with hip fracture

Inclusion Criteria:

  • Age 65 and over with hip fracture

Exclusion Criteria:

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00647309

Sheba Medical Center, Geriatric Rehabilitation dept Recruiting
Ramat Gan, Israel, 52621
Contact: Arad Marina, MD    973-3-5305108   
Principal Investigator: arad marina, MD         
Sub-Investigator: Adunsky Abraham, MD         
Sponsors and Collaborators
Sheba Medical Center
Principal Investigator: Marina Arad, MD Sheba Medical Center

Responsible Party: Dr. Marina Arad, md, Sheba Medical Center Identifier: NCT00647309     History of Changes
Other Study ID Numbers: SHEBA-08-5096-MA-CTIL
First Posted: March 31, 2008    Key Record Dates
Last Update Posted: June 12, 2012
Last Verified: June 2012

Additional relevant MeSH terms:
Fractures, Bone
Hip Fractures
Wounds and Injuries
Femoral Fractures
Hip Injuries
Leg Injuries