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Impact of Left Atrial Function on Postoperative Atrial Fibrillation

This study has been completed.
Information provided by:
Florence Nightingale Hospital, Istanbul Identifier:
First received: March 26, 2008
Last updated: June 27, 2008
Last verified: June 2008
We aimed to demonstrate the impact of left atrial functions which were evaluated by three different echocardiographic modalities , on postoperative atrial fibrillation.

Atrial Fibrillation

Study Type: Observational
Study Design: Observational Model: Case-Crossover
Time Perspective: Prospective
Official Title: Impact Of Velocity Vector Imaging, Tissue Doppler Imaging, Conventional Echocardiography And P Wave Dispertion In Evaluating Post-Operative Atrial Fibrillation After Coronary Bypass Graft Surgery

Resource links provided by NLM:

Further study details as provided by Florence Nightingale Hospital, Istanbul:

Primary Outcome Measures:
  • Velocity vector imaging derived left atrial segmenter function, Tissue doppler derved left atrial segmenter function, conventional analysis of atrial function by 2D and pulsed wave echocardiography. [ Time Frame: April 2008 ]

Estimated Enrollment: 80
Study Start Date: March 2008
Study Completion Date: May 2008
Primary Completion Date: May 2008 (Final data collection date for primary outcome measure)
Patients with postoperative atrial fibrillation
Patients without postoperative atrial fibrillation.

Detailed Description:
Postoperative atrial fibrillation after coronary artery bypass greft operation (CABG) is major complication with a prevalence of 10-50%. Although the men mechanism is not known, in recent studies, age and left atrial function have been demonstrated as the most responsible factors. Velocity vector imaging (VVI) is a new modality which may give accurate and detailed information on both left atrial segmental and global function. In this study, our aim was to assess preoperative left atrial function by using three different echocardiographic modalities, VVI, tissue Doppler imaging and conventional echocardiography and evaluate the relation between the left atrial functions and the development of post-operative atrial fibrillation after CABG.

Ages Eligible for Study:   30 Years to 80 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
Tertiary care clinic

Inclusion Criteria:

  • 1Coronary artery disease evidenced by coronary angiography
  • 2Patients with a decision of undergoing elective coronary artery bypass greft operation
  • 3Sinus rhythm in electrocardiography

Exclusion Criteria:

  • 1Rheumatic valve disease
  • 2Having prosthetic valve
  • 3CABG accompanied by other cardiac interventions (such as valvular surgery, ASD closure...etc)
  • 4Left ventricular l ejection fraction <40%
  • 5Mild to moderate mitral stenosis or regurgitation
  • 6Having atrial fibrillation or a history of atrial fibrillation attach during the last two weeks.
  • 7Congenital heart disease
  • 8Chronic liver disease
  • 9Chronic renal disease
  • 10Malignancy
  Contacts and Locations
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Please refer to this study by its identifier: NCT00646997

TC.Istanbul Bilim University, Florence Nightingale Hospital, Division of Cardiology
Istanbul, Turkey, 34381
Sponsors and Collaborators
Florence Nightingale Hospital, Istanbul
Study Director: Saide Aytekin, Professor T.C. Istanbul Bilim University, Florence Nightingale Hospital, Division of Cardiology
  More Information

Responsible Party: Prof.Dr.Saide Aytekin, T.C. Istanbul Bilim University, Florence Nightingale Hospital Identifier: NCT00646997     History of Changes
Other Study ID Numbers: YT1977/2
Study First Received: March 26, 2008
Last Updated: June 27, 2008

Keywords provided by Florence Nightingale Hospital, Istanbul:
atrial fibrillation, left atrium, velocity vector imaging

Additional relevant MeSH terms:
Atrial Fibrillation
Arrhythmias, Cardiac
Heart Diseases
Cardiovascular Diseases
Pathologic Processes processed this record on September 21, 2017