We updated the design of this site on December 18, 2017. Learn more.
ClinicalTrials.gov
ClinicalTrials.gov Menu

Cognitive Determinants of Psychoeducation and Information in Psychoses (COGPIP)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT00646256
Recruitment Status : Unknown
Verified March 2008 by German Research Foundation.
Recruitment status was:  Recruiting
First Posted : March 28, 2008
Last Update Posted : March 28, 2008
Sponsor:
Information provided by:

Study Description
Brief Summary:
The aim of the study is to examine whether the efficacy of psychoeducation in patients with schizophrenia or schizoaffective disorders is dependent on their cognitive performance level and if a preceding cognitive training can enhance the therapeutic effects of psychoeducation

Condition or disease Intervention/treatment
Schizophrenia Delusional Disorders (ICD-10) Behavioral: COGPACK training, psychoeducation

Detailed Description:
Schizophrenic inpatients are examined shortly after admission with a broad battery of clinical and neurological rating scales and neuropsychological tests. They are then randomized to either standard treatment (including antipsychotic medications, art and occupational therapy, psychotherapy) or to standard treatment plus daily computerbased cognitive training (COGPACK; ten 1-hour sessions over two weeks). After repetition of the broad assessment battery all patients (and some of their family members) take part in a bifocal psychoeducation group program (eight 1-hour sessions over four weeks). Specific pre-post measures are illness knowledge, self and expert ratings of adherence to treatment, insight to the illness, treatment satisfaction. The study also includes a 9-month follow-up, with number of rehospitalizations, days in hospital and psychopathology as the primary outcome measures.

Study Design

Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 120 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Psychoeducation in Patients With Schizophrenia: Neuropsychological Performance and Cognitive Training as Determinants of Outcome
Study Start Date : February 2006
Estimated Primary Completion Date : December 2008

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Arms and Interventions

Arm Intervention/treatment
No Intervention: no training
Experimental: COGPACK training Behavioral: COGPACK training, psychoeducation
Bifocal psychoeducation group program (Munich Psychoses Information Program - PIP) with preceding computerbased cognitive training program (COGPACK)


Outcome Measures

Primary Outcome Measures :
  1. illness knowledge, adherence to treatment, insight to the illness, satisfaction with treatment. 9-month follow-up: number of rehospitalizations, days in hospital [ Time Frame: Baseline, after cognitive training, after psychoeducation, 9-month after end of psychoeducation ]

Secondary Outcome Measures :
  1. Psychopathological status
  2. Psychosocial rehabilitation

Eligibility Criteria

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   18 Years to 60 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Inpatients
  • Informed consent
  • German as first language or very good knowledge of German

Exclusion Criteria:

  • Mental retardation
  • Any serious somatic illness
Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00646256


Contacts
Contact: Thomas Jahn, Prof. Dr. phil. Dipl.-Psych. +49 (0)89-4140 4278 th.jahn@lrz.tum.de

Locations
Germany
Klinik und Poliklinik für Psychiatrie und Psychotherapie, Klinikum rechts der Isar, Technical University of Munich Recruiting
Munich, Germany, 81675
Sponsors and Collaborators
German Research Foundation
Investigators
Principal Investigator: Thomas Jahn, Prof. Dr. phil. Dipl.-Psych. Klinik und Poliklinik für Psychiatrie und Psychotherapie, Klnikum rechts der Isar, Technbical Univesity Munich
More Information

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: Prof. Dr. phil. Dipl.-Psych. Thomas Jahn, Technical University of Munich
ClinicalTrials.gov Identifier: NCT00646256     History of Changes
Other Study ID Numbers: DFG Ja 680 / 4-2, 4-3
First Posted: March 28, 2008    Key Record Dates
Last Update Posted: March 28, 2008
Last Verified: March 2008

Keywords provided by German Research Foundation:
schizoaffective
schizotypal

Additional relevant MeSH terms:
Schizophrenia
Schizophrenia, Paranoid
Schizophrenia Spectrum and Other Psychotic Disorders
Mental Disorders