Effect of Irvingia Gabonensis (Bush Mango)on Parameters Associated With Metabolic Syndrome
|Study Design:||Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
|Official Title:||The Efficacy of Irvingia Gabonensis (Bush Mango) in the Management of Overweight, Obesity and Metabolic Syndrome in Cameroon.|
- Weight change [ Time Frame: 10 weeks ] [ Designated as safety issue: No ]
- Change in blood lipids and hormone levels [ Time Frame: 10 weeks ] [ Designated as safety issue: No ]
|Study Start Date:||November 2006|
|Study Completion Date:||April 2007|
|Primary Completion Date:||March 2007 (Final data collection date for primary outcome measure)|
Placebo Comparator: 1
Compare active to placebo
Dietary Supplement: IGOB131
Comparison of 250 mg per day of Irvingia gabonensis to placebo
To assess the effects of seeds of Irvingia gabonensis on body weight, fasting blood glucose, plasma total and LDL cholesterol in 102 overweight and obese participants.
The study was a 10 week randomized, double blind, placebo controlled design. participants were randomly divided into 2 groups of 51 participants each. Group 1 was the placebo group, while Group 2 was the active group. Each group received 2 daily doses of 125 mg (before meals) of either placebo or Irvingia gabonensis.
Weight as well as fasting blood was taken at baseline and at 4, 8 and 10 weeks. No major detary changes or exercises were suggested during the study period.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00645775
|Laboratory of Nutrition & Nutritional Biochemistry|
|Yaounde, Centre, Cameroon, BP812|
|Study Director:||Julius E Oben, PhD||Gateway Health Alliances / University of Yaounde|