T-Wave Alternans (TWA) Reproducibility in CAD Patients
Recruitment status was Not yet recruiting
Microvolt T-Wave Alternans (MTWA) is a relatively new non-invasive method for identifying patients at increased risk of sudden death from ventricular arrhythmias. MTWA can be measured during a routine exercise test, during pharmacologic stress or during cardiac pacing. Its clinical performance compares favorably with that of other non-invasive risk stratifiers and invasive electophysiologic studies. The purpose of the present study is to define the reproducibility of MTWA testing.
Coronary Artery Disease
|Study Design:||Observational Model: Case Control
Time Perspective: Prospective
|Official Title:||Reproducibility of T Wave Alternans Testing in Patients With Ischemic Heart Disease.|
- Reproducibility of TWA test results [ Time Frame: 1 week ] [ Designated as safety issue: No ]
- Ventricular arrhythmias during exercise [ Time Frame: 1 week ] [ Designated as safety issue: No ]
|Study Start Date:||May 2008|
|Estimated Study Completion Date:||May 2009|
|Estimated Primary Completion Date:||January 2009 (Final data collection date for primary outcome measure)|
The study will be performed in the Cardiac Rehabilitation Center at Assaf Harofeh Medical Center. Patients with coronary artery disease will be eligible to enroll.
Patient will undergo an exercise test on a stationary bicycle. TWA will be measured at heart rate of 105 and 115 BPM. The test will be repeated one week later in the same fashion. The patient will continue follow-up in the rehabilitation center as dictated by the rehabilitation program. Patients will be kept on their regular medications and there will be no change of the medications from the first TWA measurement to the second.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00644345
|Contact: Therese Fuchs, MDfirstname.lastname@example.org|
|Contact: Isaac Zysman, MD||972-8-977-9735||zysmanI@asaf.health.gov.il|
|Assaf Harofeh Medical Center||Not yet recruiting|
|Contact: Therese Fuchs, MD 972-8-977-9735 email@example.com|
|Contact: Isaac Zysman, MD 972-8-977-9735 zysmanI@asaf.health.gov.il|
|Principal Investigator: Therese Fuchs, MD|
|Principal Investigator:||Therese Fuchs, MD||Assaf-Harofeh Medical Center|