Milk as Treatment for Hypoglycemia

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00643110
Recruitment Status : Withdrawn (Not funded)
First Posted : March 26, 2008
Last Update Posted : March 25, 2015
Information provided by:
Creighton University

Brief Summary:
Test hypothesis that milk can raise blood sugars as well as orange juice or glucose tablets without raising blood sugars too much the way that orange juice or glucose tablets sometimes do.

Condition or disease Intervention/treatment Phase
Type 1 Diabetes Drug: D50 glucose Not Applicable

Detailed Description:
Subjects will wear a continuous glucose monitor prior to test to determine normal glucose levels. The morning of the test an IV will be inserted into the subject and insulin and saline drips will be started. Blood glucose levels will be checked every 10 minutes until the subject becomes hypoglycemic. IVs will be stopped at that time and subject will be given skim milk, orange juice or glucose tablets at that time. Blood will be drawn every 15 minutes until blood sugars stabilize. Blood draws will be analyzed to determine glucose, insulin, epinephrine, norepinephrine, glucagon, cortisol, growth hormone and GLP-1 levels. Procedure will be repeated two more times using other glucose methods (skim milk, orange juice or glucose tablets).

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 0 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Milk as Treatment for Hypoglycemia
Study Start Date : April 2008
Actual Primary Completion Date : January 2009
Actual Study Completion Date : January 2009

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Hypoglycemia

Intervention Details:
  • Drug: D50 glucose
    D50 glucose would be administered, if necessary.

Primary Outcome Measures :
  1. Completion of 6 subjects. [ Time Frame: One year ]

Information from the National Library of Medicine

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Ages Eligible for Study:   19 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Type 1 Diabetes
  • Able to be consented
  • Able to wear continuous glucose monitor

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00643110

United States, Nebraska
Creighton Diabetes Center
Omaha, Nebraska, United States, 68131
Sponsors and Collaborators
Creighton University

Responsible Party: Marc S. Rendell, M.D., Creighton University Identifier: NCT00643110     History of Changes
Other Study ID Numbers: Rendell 01
Dairy Council - Rendell 01
First Posted: March 26, 2008    Key Record Dates
Last Update Posted: March 25, 2015
Last Verified: March 2015

Keywords provided by Creighton University:

Additional relevant MeSH terms:
Diabetes Mellitus, Type 1
Diabetes Mellitus
Glucose Metabolism Disorders
Metabolic Diseases
Endocrine System Diseases
Autoimmune Diseases
Immune System Diseases