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The Effect of Caffeine Reduction on Snoring and Quality of Life

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ClinicalTrials.gov Identifier: NCT00641810
Recruitment Status : Completed
First Posted : March 24, 2008
Last Update Posted : December 31, 2013
Information provided by (Responsible Party):
Benjamin Littenberg, University of Vermont

Brief Summary:

Snoring is a problem for many people, often disturbing energy level, quality of sleep, and the relationship with a bed partner. Two observational studies that have indicated a relationship between the consumption of caffeine and snoring. The objective of this study will be to observe the degree of snoring and quality of sleep when caffeine intake is reduced over a period of four weeks. This will be a prospective, before-and-after study of a behavioral intervention.

This study will engage thirty adults who report snoring, drink two cups of coffee or more per day (or an equivalent amount of caffeine), and have a consistent bed partner who can report on snoring severity. Both subject and partner will be asked to fill out a diary each day. The subjects will record the type of caffeine consumed, time at which each beverage was ingested, the total minutes of physical exercise, any caffeine withdrawal symptoms, quality of sleep, and energy in the morning. The partner (reporter) will rate his or her own sleep quality and energy in the morning, as well as the snoring level of the subject. Beginning the second week of the study, the subject will reduce caffeine intake to half the baseline consumption, and on the third week, will eliminate caffeine altogether.

At the end of each week, the participants will be asked to mail their diaries in to the researchers and start a new series of entries. The study team will also call each week to answer any questions or concerns of the subject and reporter, and encourage continued reporting. When six weeks have elapsed following the completion of the last diary, the investigators will make a final call to the participants to record their current level of snoring, quality of sleep, and daily energy level.

Condition or disease Intervention/treatment
Snoring Behavioral: Caffeine reduction

Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 30 participants
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: The Effect of Caffeine Reduction on Snoring and Quality of Life
Study Start Date : March 2008
Primary Completion Date : June 2011
Study Completion Date : June 2011

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Caffeine Snoring
U.S. FDA Resources

Arm Intervention/treatment
Experimental: A
After one week at usual levels of caffeine use, patients are asked to reduce their caffeine consumption to no more than 2 cups of coffee (or equivalent) for one week and then to zero for two weeks.
Behavioral: Caffeine reduction
Reduction in daily caffeine consumption from usual amounts to none.

Primary Outcome Measures :
  1. Snoring [ Time Frame: 4 weeks ]

Secondary Outcome Measures :
  1. Sleep Quality [ Time Frame: 4 weeks ]

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • age at least 18 years
  • consume 16 ounces of coffee or 25 ounces of caffeinated soda or tea
  • consistent bed partner willing to serve as reporter
  • reported as a loud snorer (6 or more on 10 point scale) most days of an average week

Exclusion Criteria:

  • pregnant
  • diagnosed by doctor with sleep apnea, facial or airways defect
  • any facial or airways surgery that has changed snoring pattern.
  • upper airways infection that requires antibiotics, cough suppressants, etc. in the last month
  • use any continuous positive airway pressure (CPAP) device or dental appliance
  • bed partner hearing impairment or defects.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00641810

United States, Vermont
University of Vermont
Burlington, Vermont, United States, 05401
Sponsors and Collaborators
University of Vermont
Principal Investigator: Benjamin Littenberg, MD University of Vermont

Responsible Party: Benjamin Littenberg, Professor of Medicine, University of Vermont
ClinicalTrials.gov Identifier: NCT00641810     History of Changes
Other Study ID Numbers: 08-123
First Posted: March 24, 2008    Key Record Dates
Last Update Posted: December 31, 2013
Last Verified: December 2013

Keywords provided by Benjamin Littenberg, University of Vermont:

Additional relevant MeSH terms:
Respiratory Sounds
Signs and Symptoms, Respiratory
Signs and Symptoms
Central Nervous System Stimulants
Physiological Effects of Drugs
Phosphodiesterase Inhibitors
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action
Purinergic P1 Receptor Antagonists
Purinergic Antagonists
Purinergic Agents
Neurotransmitter Agents