Modification of Cognitive Processing Therapy (CPT-C) for PTSD and Alcohol Dependence
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|ClinicalTrials.gov Identifier: NCT00639288|
Recruitment Status : Completed
First Posted : March 20, 2008
Last Update Posted : March 21, 2016
Objective: To develop a detailed treatment manual that modifies the existing CPT-C treatment protocol to allow for concurrent treatment of PTSD and AD, and to obtain some pilot data regarding its efficacy.
Hypothesis: We predict that CPT-C will significantly reduce the number of drinking days (measured by the Timeline Follow Back Method [TLFB]) and reduce the symptoms of PTSD (measured by the [CAPS and PCL] scores).
Design: This is a non-randomized, prospective study in which all participants will receive the modified CPT-C for 12 weeks by trained CPT-C clinicians, with each session lasting approximately 1-1.5 hours). Modifications to CPT-C include psychoeducation about alcohol use as an avoidance of PTSD symptoms integrated throughout treatment, integration of coping skills training for AD, weekly breathalyzer tests to measure blood alcohol level, and use and collection of daily dairies of alcohol use.
|Condition or disease||Intervention/treatment||Phase|
|Alcohol Dependence PTSD||Other: modified CPT-C||Phase 2 Phase 3|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||9 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Official Title:||Modification of Cognitive Processing Therapy (CPT-C) for Posttraumatic Stress Disorder (PTSD) and Alcohol Dependence (AD)|
|Study Start Date :||March 2008|
|Actual Primary Completion Date :||October 2014|
|Actual Study Completion Date :||April 2015|
Other: modified CPT-C
- Alcohol use, PTSD symptoms [ Time Frame: 16 weeks ]
- quality of life [ Time Frame: 16 weeks ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00639288
|United States, Connecticut|
|VA Connecticut Healthcare System - West Haven Campus|
|West Haven, Connecticut, United States, 06516|
|Principal Investigator:||Ismene L Petrakis, MD||Yale University|