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The Effect of Myopic Optical Defocus on the Humphrey Matrix 30-2 Test

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00638430
First Posted: March 19, 2008
Last Update Posted: March 19, 2008
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
Samsung Medical Center
  Purpose
The purpose of this study is to examine the effect of the myopic optical defocus on the Humphrey Matrix 30-2 test.

Condition
Myopia

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective
Official Title: The Effect of Myopic Optical Defocus on the Humphrey Matrix 30-2 Test

Further study details as provided by Samsung Medical Center:

Primary Outcome Measures:
  • mean defect [ Time Frame: 15 minutes ]

Enrollment: 40
Study Start Date: March 2007
Study Completion Date: March 2008
Primary Completion Date: October 2007 (Final data collection date for primary outcome measure)
Groups/Cohorts
1
low myopic group
2
moderate myopic group

Detailed Description:

The Humphery Matrix (Zeiss, Dublin, California, USA; in cooperation with Welch Allyn, Skaneateles, New York, USA), which is a recently developed version of FDT perimetry, showed more improved technology to detect early glaucomatous damage. The user's guide for the Humphrey Matrix (Humphrey® matrix visual field instrument user's guide. Zeiss, Dublin, California, USA; in cooperation with Welch Allyn, Skaneateles, New York, USA; 2003) suggests that myopic refractive errors more than -3.0 D need to be corrected before the 30-2 test. However, the proper correction of the optical defocus is not always easy because of a lack of trial frame.

The purpose of the present study is twofold. At first, the influence of the low-grade myopia on the Humphery Matrix 30-2 test will be evaluated and compared to the effect of moderate-grade myopia. Secondly, the influence of myopic optical defocus and the glaucomatous visual field damage on the pattern deviation plot change according to the severity of glaucomatous visual field damage will be estimated.

  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   27 Years to 61 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
tertiary care clinic
Criteria

Inclusion Criteria:

  • intra-ocular pressure 23 or higher
  • suspicious glaucomatous optic disc change
  • suspicious defect of retinal nerve fiber layer
  • or eyes with various degrees of glaucoma

Exclusion Criteria:

  • a high myopic eye (SE more than -6.0 D)
  • moderate to severe cataract
  • evidence of diabetic or hypertensive retinopathy
  • macular disease
  • intra-ocular inflammation
  • history of intraocular surgery and any other ocular lesion that could have an influence on the perimetry result
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00638430


Locations
Korea, Republic of
Samsung Medical Center
Seoul, Korea, Republic of, 130-710
Sponsors and Collaborators
Samsung Medical Center
Investigators
Study Chair: Changwon Kee, M.D. Department of Ophthalmology, Samsung Medical Center,
  More Information

Publications:
Responsible Party: Changwon Kee, Department of Ophthalmology, Samsung Medical Center,
ClinicalTrials.gov Identifier: NCT00638430     History of Changes
Other Study ID Numbers: Humphrey30-2
First Submitted: March 12, 2008
First Posted: March 19, 2008
Last Update Posted: March 19, 2008
Last Verified: March 2008

Keywords provided by Samsung Medical Center:
myopia
Humphery Matrix 30-2 test

Additional relevant MeSH terms:
Myopia
Refractive Errors
Eye Diseases