We are updating the design of this site. Learn more.
Show more
ClinicalTrials.gov
ClinicalTrials.gov Menu

A Randomised Comparison on the Dose Requirement Between, Levobupivacaine, Ropivacaine and Bupivacaine in Intrathecal Anaesthesia

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00636974
First Posted: March 17, 2008
Last Update Posted: October 23, 2013
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
Hospital Authority, Hong Kong
  Purpose
To determine and compare the effective intrathecal dose of levobupivacaine, ropivacaine and bupivacaine for 50% of patients in lower limb surgery

Condition Intervention
Anesthesia, Conduction Surgery Procedure: Combined spinal epidural anaesthesia

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double
Primary Purpose: Treatment
Official Title: Minimum Local Anaesthetic Dose for Intrathecal Anaesthesia: a Randomised Comparison Between Levobupivacaine, Ropivacaine and Bupivacaine

Resource links provided by NLM:


Further study details as provided by Hospital Authority, Hong Kong:

Primary Outcome Measures:
  • Sensory block at 12th thoracic dermatome or above and successful conduct of the lower limb surgery up to 50 minutes after the intrathecal injection of the study drug [ Time Frame: 50 minutes after the intrathecal injection of the study drug ]

Estimated Enrollment: 75
Study Start Date: January 2006
Study Completion Date: July 2008
  Eligibility

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Criteria

Inclusion Criteria:

  • body weight=40-90kg,
  • height higher than 145cm

Exclusion Criteria:

  • Known hypersensitivity to amide local anaesthetics,
  • patients who do not understand English and Chinese,
  • Body mass index higher than 35 kg per sq metre
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00636974


Locations
China
Kwong Wah Hospital
Hong Kong, China
Sponsors and Collaborators
Hospital Authority, Hong Kong
Investigators
Principal Investigator: Ying Yin Lee, Dr Department of Anaesthesiology, Kwong Wah Hospital
  More Information

Additional Information:
ClinicalTrials.gov Identifier: NCT00636974     History of Changes
Other Study ID Numbers: KW/FR/05-025
HARECCTR0500056
First Submitted: December 19, 2007
First Posted: March 17, 2008
Last Update Posted: October 23, 2013
Last Verified: October 2013

Keywords provided by Hospital Authority, Hong Kong:
Patients who are going to have regional anaesthesia for lower limbs surgery.
Leg Surgery.

Additional relevant MeSH terms:
Anesthetics
Bupivacaine
Ropivacaine
Levobupivacaine
Central Nervous System Depressants
Physiological Effects of Drugs
Anesthetics, Local
Sensory System Agents
Peripheral Nervous System Agents