A Pilot Study to Evaluate Optical Spectroscopy of Pigmented Skin Lesions
The purpose of this study is to evaluate the physiological correlates of imaging devices,Modified Two Layer Diffuse Optical Spectroscopy (MTL DOS ) in the evaluation of atypical moles and melanoma.
A typical moles and melanoma will have a different optical profile based on physiological parameters compared to benign nevus.
The first measured is to determine the hardware variability. From this optical data, a "correction" curve will be developed and this will be applied to all subsequent optical measurements.
|Study Design:||Observational Model: Case Control
Time Perspective: Prospective
|Official Title:||A Pilot Study to Evaluate the Correlation Between Modified Two Layer Diffuse Optical Spectroscopy With the Clinical and Histological Examinations of Pigmented Skin Lesions Based on Physiological Parameters|
- establish the variance of optical measurements in human pigmented lesions (benign and malignant). [ Time Frame: 24 hours ] [ Designated as safety issue: Yes ]
|Study Start Date:||July 2008|
|Study Completion Date:||November 2013|
|Primary Completion Date:||November 2013 (Final data collection date for primary outcome measure)|
Device: optical imaging
The researcher using special imaging devices to obtain information about a typical mole and melanoma and use this information to determine the different between malignant and benign melanized lesions.
Specifically,to compare malignant vs. benign lesions.
The skin lesion will be exam and diagnose by the physician. The picture will be obtain by the technician use these two devices before and after the treatment of the lesion.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00633516
|United States, California|
|Beckman Laser Medical clinic, UCI|
|Irvine, California, United States, 92612|
|Orange, California, United States, 92868|
|Principal Investigator:||David JB Hsiang, MD||Beckman Laser Institute University of California Irvine|