The Correlation Between Oxidative Stress and Indinated Contrast-Media Nephrotoxicity
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT00632892|
Recruitment Status : Completed
First Posted : March 11, 2008
Last Update Posted : March 11, 2008
Clinically, iodinated contrast-medium (CM) is widely used in angiography and computerized tomography. CM-induced nephropathy (CMIN) is one major complication after application of CM. Therefore, how to prevent CMIN is always one of the hot topics concerned by nephrologists, cardiologists, and radiologists.
The present study is aimed to determine the norepinephrine concentration, oxidative markers, and tubular damage markers in the urine samples of patients undergoing intravenous pyelography (IVP).
The working hypothesis is high-osmolarity contrast media (HOCM) causes more oxidative stress and greater tubular damage than iso-osmolarity contrast media (IOCM).
|Condition or disease|
|Study Type :||Observational|
|Enrollment :||80 participants|
|Official Title:||The Correlation Between Oxidative Stress and Indinated Contrast-Media Nephrotoxicity|
|Study Start Date :||December 2007|
|Actual Primary Completion Date :||January 2008|
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00632892
|Far Eastern Memorial Hospital|
|Pan Chiao, Taipei, Taiwan, 220|