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Trial record 2 of 2 for:    "Pneumonia eosinophilic"

The Efficacy of Three Months-prednisolone Therapy for Chronic Eosinophilic Pneumonia

This study has been completed.
Information provided by (Responsible Party):
Naoki Inui, Hamamatsu University Identifier:
First received: February 28, 2008
Last updated: September 18, 2014
Last verified: September 2014
A comparison of 3 months-prednisolone administration with 6 months-prednisolone therapy in the treatment of chronic eosinophilic pneumonia. Three months-prednisolone administration may be as effective as 6 months-therapy.

Condition Intervention Phase
Eosinophilic Pneumonia
Chronic Disease
Drug: prednisolone 0.5 mg/kg/day for three months
Drug: prednisolone 0.5 mg/kg/day for six months
Phase 4

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Phase 4, Randomized Study of Three Months-prednisolone Therapy in the Treatment of Chronic Eosinophilic Pneumonia

Resource links provided by NLM:

Further study details as provided by Naoki Inui, Hamamatsu University:

Primary Outcome Measures:
  • Efficacy of 3 versus 6 months-prednisolone therapy for chronic eosinophilic pneumonia [ Time Frame: Three years ]

Secondary Outcome Measures:
  • Safety of 3 versus 6 months-prednisolone therapy for chronic eosinophilic pneumonia [ Time Frame: Three years ]

Estimated Enrollment: 50
Study Start Date: June 2008
Study Completion Date: March 2010
Primary Completion Date: March 2010 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: 1
prednisolone therapy for three months
Drug: prednisolone 0.5 mg/kg/day for three months
period of treatment
Other Name: prednisolone
Active Comparator: 2
prednisolone therapy for six months
Drug: prednisolone 0.5 mg/kg/day for six months
period of therapy
Other Name: prednisolone


Ages Eligible for Study:   16 Years to 80 Years   (Child, Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Biopsy-proven chronic eosinophilic pneumonia

Exclusion Criteria:

  • Patients who received oral glucocorticosteroid (more than 10 mg)
  • Immunosuppressive drug
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Please refer to this study by its identifier: NCT00632554

Hamamatsu University School of Medicine
Hamamatsu, Japan
Sponsors and Collaborators
Hamamatsu University
Study Chair: Kingo Chida, MD, PhD Hamamatsu University
  More Information

Publications automatically indexed to this study by Identifier (NCT Number):
Responsible Party: Naoki Inui, Department of Respiratory Medicine, Hamamatsu University Identifier: NCT00632554     History of Changes
Other Study ID Numbers: Hamamatsu-18-67
Study First Received: February 28, 2008
Last Updated: September 18, 2014

Additional relevant MeSH terms:
Chronic Disease
Pulmonary Eosinophilia
Lung Diseases
Respiratory Tract Diseases
Respiratory Tract Infections
Disease Attributes
Pathologic Processes
Hypereosinophilic Syndrome
Leukocyte Disorders
Hematologic Diseases
Prednisolone acetate
Methylprednisolone acetate
Methylprednisolone Hemisuccinate
Prednisolone hemisuccinate
Prednisolone phosphate
Anti-Inflammatory Agents
Hormones, Hormone Substitutes, and Hormone Antagonists
Physiological Effects of Drugs
Antineoplastic Agents, Hormonal
Antineoplastic Agents
Autonomic Agents
Peripheral Nervous System Agents
Gastrointestinal Agents processed this record on May 25, 2017