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Studies of Neuroendocrine and Energy Metabolism in Patients With Eating Disorders

This study has been completed.
Information provided by:
National Taiwan University Hospital Identifier:
First received: March 3, 2008
Last updated: March 1, 2009
Last verified: March 2009
This study aims to investigate neuroendocrine, autonomic functioning, and energy metabolism in patients with eating disorder and their relationships with psychopathology of eating disorders (eating patterns, depression, and personality) in these patients.

Anorexia Nervosa
Bulimia Nervosa

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Cross-Sectional
Official Title: Studies of Neuroendocrine and Energy Metabolism in Patients With Eating Disorders

Resource links provided by NLM:

Further study details as provided by National Taiwan University Hospital:

Biospecimen Retention:   Samples Without DNA

Enrollment: 112
Study Start Date: May 2007
Study Completion Date: January 2009
Primary Completion Date: January 2009 (Final data collection date for primary outcome measure)

Detailed Description:
The study subjects include female patients with DSM-IV diagnosis of AN (n = 30), BN (n = 60) and age-controled normal subjects (n = 30). They will receive a clinical interview and are asked to complete several self-administered questionnaires which included eating-related questionnaires, general psychological functioning scales and personality scales. After overnight fast, each subject undergoes a blood sample collection for neuroendocrine examination, body composition examination using BIA method, basal metabolic rate measurement by indirect calorimetry, and ECG in the morning between 0800 and 0900. Clinical patients would be asked to repeat filling the self-rating scales, weight and body fat measurement, as well as blood drawing again 2 months after treatment.

Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
patients with eating disorders and normal controls

Inclusion Criteria:

  • Subjects who fulfilled DSM-IV diagnosis of anorexia nervosa or bulimia nervosa
  • Normal controls

Exclusion Criteria:

  • Any major psychiatric disorders
  • Use of psychoactive medications
  • Drug and alcohol abuse
  • Medical problems (cardiovascular condition and endocrine disorders)
  Contacts and Locations
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Please refer to this study by its identifier: NCT00631605

National Taiwan University Hospital
Taipei, Taiwan
Sponsors and Collaborators
National Taiwan University Hospital
Principal Investigator: Mei-Chih Tseng, MD, Msc National Taiwan University Hospital
  More Information

Responsible Party: Mei-Chih Tseng/Attending psychiatrist, National Taiwan University Hospital Identifier: NCT00631605     History of Changes
Other Study ID Numbers: 200705061R
Study First Received: March 3, 2008
Last Updated: March 1, 2009

Keywords provided by National Taiwan University Hospital:
eating disorders

Additional relevant MeSH terms:
Feeding and Eating Disorders
Anorexia Nervosa
Bulimia Nervosa
Mental Disorders
Signs and Symptoms, Digestive
Signs and Symptoms
Hyperphagia processed this record on May 25, 2017