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Genetic Polymorphysm of Cholesterol 24 S Hydroxylase in Patients With Glaucoma and AMD
This study has been completed.
Sponsor:
Centre Hospitalier Universitaire Dijon
Information provided by:
Centre Hospitalier Universitaire Dijon
ClinicalTrials.gov Identifier:
NCT00629044
First received: February 25, 2008
Last updated: March 25, 2011
Last verified: August 2009
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Purpose
The aim of this study is to assess the implicitement of the cholesterol 24 S hydroxylase gene and the 24 S hydroxycholesterol in glaucoma and in age related macular degeneration.
| Condition | Intervention |
|---|---|
| Glaucoma | Biological: Assessing the blood level of cholesterol 24 S Hydroxylase Biological: Assessing the blood level of cholesterol 24 S hydroxylase Biological: assessing the blood level of cholesterol 24 S hydroxylase |
| Study Type: | Interventional |
| Study Design: | Allocation: Non-Randomized Intervention Model: Parallel Assignment Masking: Open Label Primary Purpose: Screening |
| Official Title: | Etude du Polymorphysme génétique de la cholestérol 24S Hydroxylase et Des Teneurs en 24S hydroxycholestérol Chez Des Patients Atteints de Glaucome ou de dégénérescence Maculaire liée à l'âge. |
Resource links provided by NLM:
Further study details as provided by Centre Hospitalier Universitaire Dijon:
Primary Outcome Measures:
- To know if cholesterol 24 S hydroxylase and 24 hydroxycholesterol are involve in Glaucoma and AMD [ Time Frame: 2 years ]
| Estimated Enrollment: | 320 |
| Study Start Date: | November 2007 |
| Study Completion Date: | January 2011 |
| Primary Completion Date: | November 2009 (Final data collection date for primary outcome measure) |
| Arms | Assigned Interventions |
|---|---|
| Active Comparator: G |
Biological: Assessing the blood level of cholesterol 24 S Hydroxylase
Comparison of venous blood level of Cholesterol 24 S hydroxylase and 24 hydroxycholesterol in patients with Glaucoma and AMD and in healthy subjects.
|
| Active Comparator: AMD |
Biological: Assessing the blood level of cholesterol 24 S hydroxylase
Comparison of venous blood level of cholesterol 24 S hydroxylase and 24 hydroxycholesterol in patients with Glaucoma, AMD end in healthy subjects
|
| Active Comparator: Healthy subjects |
Biological: assessing the blood level of cholesterol 24 S hydroxylase
Comparison of venous blood level of cholesterol 24 S hydroxylase and 24 hydroxycholesterol in patients with glaucoma, AMD and in healthy subjects
|
Eligibility| Ages Eligible for Study: | 40 Years and older (Adult, Senior) |
| Sexes Eligible for Study: | All |
| Accepts Healthy Volunteers: | Yes |
Criteria
Inclusion Criteria:
- Patient with Glaucoma
- Patient with AMD
- Healthy patient
Exclusion Criteria:
- All patients who use any treatment in order to maintain in normal value their blood cholesterol
Contacts and Locations
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Please refer to this study by its ClinicalTrials.gov identifier: NCT00629044
Please refer to this study by its ClinicalTrials.gov identifier: NCT00629044
Locations
| France | |
| Ophthalmology Unit CHU Dijon | |
| Dijon, Burgundy, France, 21000 | |
Sponsors and Collaborators
Centre Hospitalier Universitaire Dijon
Investigators
| Principal Investigator: | Catherine Creuzot-Gracher, MD, PhD | CHU Dijon |
More Information
Publications:
| Responsible Party: | Professor Catherine Creuzot-Garcher, CHU Dijon |
| ClinicalTrials.gov Identifier: | NCT00629044 History of Changes |
| Other Study ID Numbers: |
PHRC IR 2006 |
| Study First Received: | February 25, 2008 |
| Last Updated: | March 25, 2011 |
Additional relevant MeSH terms:
|
Glaucoma Ocular Hypertension Eye Diseases |
ClinicalTrials.gov processed this record on July 27, 2017