Genetic Polymorphysm of Cholesterol 24 S Hydroxylase in Patients With Glaucoma and AMD
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ClinicalTrials.gov Identifier: NCT00629044 |
Recruitment Status
:
Completed
First Posted
: March 5, 2008
Last Update Posted
: March 28, 2011
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Condition or disease | Intervention/treatment | Phase |
---|---|---|
Glaucoma | Biological: Assessing the blood level of cholesterol 24 S Hydroxylase Biological: Assessing the blood level of cholesterol 24 S hydroxylase Biological: assessing the blood level of cholesterol 24 S hydroxylase | Not Applicable |
Study Type : | Interventional (Clinical Trial) |
Estimated Enrollment : | 320 participants |
Allocation: | Non-Randomized |
Intervention Model: | Parallel Assignment |
Masking: | None (Open Label) |
Primary Purpose: | Screening |
Official Title: | Etude du Polymorphysme génétique de la cholestérol 24S Hydroxylase et Des Teneurs en 24S hydroxycholestérol Chez Des Patients Atteints de Glaucome ou de dégénérescence Maculaire liée à l'âge. |
Study Start Date : | November 2007 |
Actual Primary Completion Date : | November 2009 |
Actual Study Completion Date : | January 2011 |

Arm | Intervention/treatment |
---|---|
Active Comparator: G |
Biological: Assessing the blood level of cholesterol 24 S Hydroxylase
Comparison of venous blood level of Cholesterol 24 S hydroxylase and 24 hydroxycholesterol in patients with Glaucoma and AMD and in healthy subjects.
|
Active Comparator: AMD |
Biological: Assessing the blood level of cholesterol 24 S hydroxylase
Comparison of venous blood level of cholesterol 24 S hydroxylase and 24 hydroxycholesterol in patients with Glaucoma, AMD end in healthy subjects
|
Active Comparator: Healthy subjects |
Biological: assessing the blood level of cholesterol 24 S hydroxylase
Comparison of venous blood level of cholesterol 24 S hydroxylase and 24 hydroxycholesterol in patients with glaucoma, AMD and in healthy subjects
|
- To know if cholesterol 24 S hydroxylase and 24 hydroxycholesterol are involve in Glaucoma and AMD [ Time Frame: 2 years ]

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Ages Eligible for Study: | 40 Years and older (Adult, Senior) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | Yes |
Inclusion Criteria:
- Patient with Glaucoma
- Patient with AMD
- Healthy patient
Exclusion Criteria:
- All patients who use any treatment in order to maintain in normal value their blood cholesterol

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00629044
France | |
Ophthalmology Unit CHU Dijon | |
Dijon, Burgundy, France, 21000 |
Principal Investigator: | Catherine Creuzot-Gracher, MD, PhD | CHU Dijon |
Publications:
Responsible Party: | Professor Catherine Creuzot-Garcher, CHU Dijon |
ClinicalTrials.gov Identifier: | NCT00629044 History of Changes |
Other Study ID Numbers: |
PHRC IR 2006 |
First Posted: | March 5, 2008 Key Record Dates |
Last Update Posted: | March 28, 2011 |
Last Verified: | August 2009 |
Additional relevant MeSH terms:
Glaucoma Ocular Hypertension Eye Diseases |