Novel Technique for Botulinum Toxin Injection to Minimize Patient Discomfort
|Study Design:||Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: Single Blind (Subject)
Primary Purpose: Supportive Care
|Official Title:||Novel Technique for Botulinum Toxin Injection to Minimize Patient Discomfort|
- Decrease pain on injection for treatment intervention assessed on a 10 point scale [ Time Frame: At time of intervention ] [ Designated as safety issue: No ]
|Study Start Date:||January 2007|
|Study Completion Date:||May 2007|
|Primary Completion Date:||May 2007 (Final data collection date for primary outcome measure)|
Drug: botulinum type a
Objective: To investigate whether injection of botulinum toxin type A is less painful if performed through follicular openings versus traditional non-specific approach.
Design: Prospective, randomized, single-blinded study.
Setting: Academic dermatology department.
Patients: A volunteer sample of twenty female patients aged 25-55 who had no prior history of botulinum toxin injection.
Intervention: Each patient received six randomized injections of botulinum toxin type A (Botox® Allergan). Two injections into the procerus muscle and two into each corrugator muscle. Three of the injections were performed through follicular openings and three were performed traditionally.
Main Outcome Measure: Patient discomfort on a 1-10 scale and direct comparison between the two injection techniques.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00628472
|United States, Michigan|
|Henry Ford Health System|
|Detroit, Michigan, United States, 48202|
|Principal Investigator:||David M Ozog, MD||Henry Ford Health System|