Labor Analgesia With Ropivacaine and Clonidine (LA)
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ClinicalTrials.gov Identifier: NCT00626977 |
Recruitment Status :
Completed
First Posted : February 29, 2008
Last Update Posted : July 8, 2015
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Condition or disease | Intervention/treatment |
---|---|
Labor Pain | Drug: ropivacaine Drug: ropivacaine and clonidine |
Study Type : | Observational |
Actual Enrollment : | 32 participants |
Observational Model: | Cohort |
Time Perspective: | Prospective |
Official Title: | Labor Analgesia With Ropivacaine Added to Clonidine. A Randomized Clinical Trial |
Study Start Date : | May 2000 |
Actual Primary Completion Date : | May 2000 |
Actual Study Completion Date : | December 2001 |

Group/Cohort | Intervention/treatment |
---|---|
R
R group:15 mL of 0.125% ropivacaine (18.75 mg)
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Drug: ropivacaine
15 ml of ropivacaine 0.125% peridural once |
RC
RC group:0.0625% ropivacaine (9.375 mg) plus 75 ug clonidine
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Drug: ropivacaine and clonidine
15 ml of ropivacaine 0.0625% plus 75 mcg clonidine |

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Ages Eligible for Study: | Child, Adult, Older Adult |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | Yes |
Sampling Method: | Probability Sample |
Inclusion Criteria:
- Singleton healthy
- Full-term pregnancy
- American Society of Anesthesiologists physical status I or II
Exclusion Criteria:
- Patients who had received opioids
- History of hypersensitivity to local anesthetic or to clonidine
- Fetus showed signs of possible intrauterine suffering
- Fetus showed signs of possible neurological deficit

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00626977
Brazil | |
College of Medicine of Botucatu | |
Botucatu, São Paulo, Brazil, 18618970 |
Principal Investigator: | Giane Nakamura, MD PHd | College Study of Medicine |
Responsible Party: | Yara Marcondes Machado Castiglia, MD PhD, UPECLIN HC FM Botucatu Unesp |
ClinicalTrials.gov Identifier: | NCT00626977 |
Other Study ID Numbers: |
upeclin/HC/FMB-Unesp-07 |
First Posted: | February 29, 2008 Key Record Dates |
Last Update Posted: | July 8, 2015 |
Last Verified: | February 2008 |
Analgesia Obstetrical Anesthesia Epidural Newborn |
Anesthetics, local Clonidine Pregnant women Infant, newborn |
Labor Pain Pain Neurologic Manifestations Clonidine Ropivacaine Anesthetics, Local Anesthetics Central Nervous System Depressants Physiological Effects of Drugs Sensory System Agents Peripheral Nervous System Agents |
Analgesics Antihypertensive Agents Sympatholytics Autonomic Agents Adrenergic alpha-2 Receptor Agonists Adrenergic alpha-Agonists Adrenergic Agonists Adrenergic Agents Neurotransmitter Agents Molecular Mechanisms of Pharmacological Action |