Long Term Follow-up of Bone Mineral Density in Hormone Treated Turner Syndrome
Recruitment status was: Active, not recruiting
Turner Syndrome (TS) is associated with osteopenia and osteoporosis. Reduced bone mineral density (BMD) and increased risk of fractures are present in many younger and middle-aged women with TS. The objective is therefore to describe longitudinal changes in BMD in TS.
The study is an observational follow-up study. Examinations at baseline, after 5 and 10 years.
Bone mineral density is measured by dual energy x-ray absorptiometry (DEXA) and bone turnover by bone markers.
Main Outcome Measures: Bone mineral density (BMD; grams/ square centimetre) were measured at lumbar spine, hip and the non-dominant forearm.
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Long Term Follow-up of Bone Mineral Density in Hormone Treated Turner Syndrome|
- Bone Mineral Density in columna lumbalis, collum femoris and distal ulnae Bone mineral density (BMD; grams/ square centimetre) were measured at lumbar spine, hip and the non-dominant forearm. [ Time Frame: Evey 5 years ] [ Designated as safety issue: No ]
Biospecimen Retention: Samples Without DNA
|Study Start Date:||November 1994|
|Estimated Study Completion Date:||June 2010|
|Primary Completion Date:||October 1996 (Final data collection date for primary outcome measure)|
Women with Turner syndrome
Healthy control women
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