Follow-up of Serum Androgen Profile After Bariatric Surgery in Men With Obesity Related Hypogonadotropic Hypogonadism

This study has been completed.
Information provided by:
Rijnstate Hospital Identifier:
First received: February 15, 2008
Last updated: November 5, 2014
Last verified: November 2014

The purpose of this study is to determine the natural course of the androgen profile after bariatric surgery in men with obesity related hypogonadotropic hypogonadism.

Morbid Obesity

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Follow-up of Serum Androgen Profile After Bariatric Surgery in Men With Obesity Related Hypogonadotropic Hypogonadism

Resource links provided by NLM:

Further study details as provided by Rijnstate Hospital:

Biospecimen Retention:   Samples Without DNA


Enrollment: 24
Study Start Date: September 2009
Study Completion Date: March 2011
Primary Completion Date: March 2011 (Final data collection date for primary outcome measure)
Eugonadal men with "Lapband"
Hypogonadal men with "Lapband"
Eugonadal men with gastric bypass procedure
Hypogonadal men with gastric bypass procedure


Ages Eligible for Study:   20 Years to 55 Years
Genders Eligible for Study:   Male
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

Men with planned bariatric surgery


Inclusion Criteria:

  • Male
  • Age 20-55 years
  • Planned bariatric procedure
  • Helicobacter pylori negative or adequate HP eradication

Exclusion Criteria:

  • Liver and/or kidney dysfunction
  • Psychiatric disease
  • Medication influencing androgen profile and/or bone metabolism
  • Weight > 160 kg
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00624624

Rijnstate Hospital
Arnhem, Netherlands, 6800 TA
Sponsors and Collaborators
Rijnstate Hospital
Principal Investigator: H de Boer, MD, PhD Rijnstate Hospital
  More Information

No publications provided Identifier: NCT00624624     History of Changes
Other Study ID Numbers: LTC-472-120607
Study First Received: February 15, 2008
Last Updated: November 5, 2014
Health Authority: Netherlands: Dutch Health Care Inspectorate

Keywords provided by Rijnstate Hospital:
hypogonadotropic hypogonadism
bariatric surgery
serum androgen levels
bone density

Additional relevant MeSH terms:
Endocrine System Diseases
Gonadal Disorders processed this record on March 30, 2015