Inert Dusts and Pathology of Chronic Obstructive Pulmonary Disease
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government.
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The main objective of the study is the exploration of the natural course of COPD and its biological background. To this end, active workers without COPD and workers in functional classes GOLD 0-III are investigated by a combined clinical and molecular approach. The study has been designed as a prospective, intraindividual pilot in 160 male or female volunteers of the greater Vienna Area over a period of three years for each individual volunteer.
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Ages Eligible for Study:
18 Years to 65 Years (Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Community sample of workers from the greater Vienna area
Workers of the greater Vienna Area
Current smokers or ex-smokers
Major cardiovascular diseases, in particular stroke and myocardial infarction with reduced cardiac function
Age > 65 years
Acute or chronic bronchial infection, in particular bronchiectasis